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Displaying results 1771 - 1780 of 10000 in total
  1. Drug

    Ibrexafungerp

    go.drugbank.com/drugs/DB12471
    Approved

    Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast … [A235414,L34349] Ibrexafungerp was granted FDA approval on 1 June 2021.[L34349]

    Synonyms: (1S,4AR,6AS,7R,8R,10AR,10BR,12AR,14R,15R)-15-((2R)- 2-AMINO-2,3,3-TRIMETHYLBUTOXY)-1,6A,8,10A-TETRAMETHYL-8- ((2R)-3-METHYLBUTAN-2-YL)-14-(5-(PYRIDIN-4-YL)-1H-1,2,4- TRIAZOL-1-YL)-1,6,6A,7,8,9,10,10A,10B, enfumafungin derivative B-(1,3)-D-glucan synthestis inhibitorCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  2. Drug

    Rezvilutamide

    go.drugbank.com/drugs/DB19133
    Investigational

    Rezvilutamide is under investigation in clinical trial NCT05956639 (Comparing a 6-month vs Long-term Course of Rezvilutamide With ADT Plus Chemotherapy in Mhspc).

    Synonyms: 4-(3-(4-((s)-2,3-dihydroxypropoxy)phenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile, Benzonitrile, 4-(3-(4-((2s)-2,3-dihydroxypropoxy)phenyl)-4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl)-
  3. Drug

    Azafenidin

    go.drugbank.com/drugs/DB19031
    Investigational

    Azafenidin is under investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")).

    Synonyms: 2-(2,4-dichloro-5-(2-propynyloxy)phenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one, 2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one
  4. Drug

    6-[18F]-Fluoro-L-m-tyrosine

    go.drugbank.com/drugs/DB17621
    Experimental

    Synonyms: 2-fluoro-5-hydroxy-l-phenylalanine F-18, L-phenylalanine, 2-fluoro-5-hydroxy-F-18
  5. Drug

    Zabedosertib

    go.drugbank.com/drugs/DB18767
    Investigational

    Synonyms: 2-pyridinecarboxamide, n-(6-(1-hydroxy-1-methylethyl)-2-(2-(methylsulfonyl)ethyl)-2h-indazol-5-yl)-6-(trifluoromethyl)-, N-(6-(1-hydroxy-1-methylethyl)-2-(2-(methylsulfonyl)ethyl)-2h-indazol-5-yl)-6-(trifluoromethyl)-2-pyridinecarboxamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    VEGFR 2 Kinase inhibitor I

    go.drugbank.com/drugs/DB17061
    Experimental

    Synonyms: 3-(2,4-dimethyl-3-ethoxycarbonylpyrrol-5-methylidenyl)-2-indolinone, Ethyl 2,4-dimethyl-5-(((3z)-2-oxo-2,3-dihydro-1h-indol-3-ylidene)methyl)-1h-pyrrole-3-carboxylate
  7. Drug

    Denfivontinib

    go.drugbank.com/drugs/DB17159
    Investigational

    Synonyms: G-749, 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one
  8. Drug

    PF-07059013

    go.drugbank.com/drugs/DB18122
    Investigational

    Synonyms: 2(1h)-pyridinone, 6-((1s)-1-((2-amino-6-fluoro-3-quinolinyl)oxy)ethyl)-5-(1h-pyrazol-1-yl)-, 6-((1s)-1-((2-amino-6-fluoroquinolin-3-yl)oxy)ethyl)-5-(1h-pyrazol-1-yl)pyridin-2(1h)-one
  9. Drug

    6-ethyl-5-[(2S)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB08099
    Experimental

    6-ethyl-5-[(2s)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamine is a solid. This compound belongs to the phenylquinolines. … These are heterocyclic compounds containing a quinoline moiety substituted with a phenyl group. This substance targets the protein renin.

    Synonyms: 6-ethyl-5-[(2S)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamine
  10. Drug

    Methylone

    go.drugbank.com/drugs/DB19192
    Investigational

    Methylone is under investigation in clinical trial NCT05741710 (A Study to Assess the use of Methylone in the Treatment of PTSD).

    Synonyms: 1-propanone, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)-, 3,4-methylenedioxy-n-methylcathinoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates