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Rezvilutamide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

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Data Packages
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Identification

Generic Name
Rezvilutamide
DrugBank Accession Number
DB19133
Background

Rezvilutamide is under investigation in clinical trial NCT05956639 (Comparing a 6-month vs Long-term Course of Rezvilutamide With ADT Plus Chemotherapy in Mhspc).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 479.47
Monoisotopic: 479.112661799
Chemical Formula
C22H20F3N3O4S
Synonyms
  • 4-(3-(4-((s)-2,3-dihydroxypropoxy)phenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
  • Benzonitrile, 4-(3-(4-((2s)-2,3-dihydroxypropoxy)phenyl)-4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl)-
External IDs
  • SHR 3680
  • SHR-3680
  • SHR3680
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
70FJN2AW22
CAS number
1572045-62-5
InChI Key
KRBMOYIWQCZVHA-INIZCTEOSA-N
InChI
InChI=1S/C22H20F3N3O4S/c1-21(2)19(31)27(15-4-3-13(10-26)18(9-15)22(23,24)25)20(33)28(21)14-5-7-17(8-6-14)32-12-16(30)11-29/h3-9,16,29-30H,11-12H2,1-2H3/t16-/m0/s1
IUPAC Name
SMILES
CC1(C)N(C(=S)N(C1=O)C1=CC=C(C#N)C(=C1)C(F)(F)F)C1=CC=C(OC[C@@H](O)CO)C=C1

References

General References
Not Available
ChemSpider
115009509
ChEMBL
CHEMBL4650276
Wikipedia
Rezvilutamide

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
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3Active Not RecruitingTreatmentHormone-dependent prostate cancer / Prostate Cancer1somestatusstop reasonjust information to hide
3RecruitingTreatmentChemotherapy Effects / Hormone Sensitive Prostate Cancer / Metastatic Prostate Cancer1somestatusstop reasonjust information to hide
3RecruitingTreatmentMetastatic Hormone-Sensitive Prostate Cancer (mHSPC)1somestatusstop reasonjust information to hide
3RecruitingTreatmentPatients With High-risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy1somestatusstop reasonjust information to hide
2Not Yet RecruitingTreatmentMetastatic Hormone-Sensitive Prostate Cancer (mHSPC)1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at July 04, 2024 20:03 / Updated at July 05, 2024 04:36