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Ansuvimab
go.drugbank.com/drugs/DB16385Approved[A225933] Ansuvimab, formerly mAb114, is a fully human IgG1 mAb derived from a survivor of the 1995 Kikwit EBOV outbreak 11 years after infection, which displays strong glycan-independent binding to a … Ansuvimab is just the second FDA-approved treatment for EVD.[L29560]
Categories: Antiinfectives for Systemic Use, Treatments for Ebola Virus Disease4-(Isopropylamino)diphenylamine
go.drugbank.com/drugs/DB14195ApprovedSensitivity to this compound may be identified with a clinical patch test. … 4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen.
Synonyms: N-Fenyl-N'-isopropyl-p-fenylendiamin, N-Isopropyl-N'-phenyl-p-phenylenediamineDimetindene
go.drugbank.com/drugs/DB08801ApprovedInvestigationalDimetindene (Fenistil) is an antihistamine/anticholinergic used orally and locally as an antipruritic.
Categories: Antihistamines for Topical Use, Antihistamines for Systemic UseValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigationalValsartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions. … [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension in adults. Shortly after, in 1997, this drug was approved in the United States.
Mixtures: VALSARTAN COMP PU 160/12.5, VALSARTAN COMP PU 160/12.5Categories: Antihypertensive Agents Indicated for Hypertension, Cytochrome P-450 SubstratesDoxecitine
go.drugbank.com/drugs/DB02594ApprovedInvestigationalIt is an essential component of the deoxyribonucleotide pool required for DNA synthesis and repair. … This combination is the first and only approved treatment for Thymidine Kinase 2 deficiency.[L54613, L54618]
Bronopol
go.drugbank.com/drugs/DB13960ApprovedThe agent is largely available commercially as an antibacterial for a variety of industrial purposes while it is predominantly available for purchase as a pet animal litter antibacterial at the domestic … re-evaluations of bronopol use in large markets such as Canada now place various compositional and product restrictions on the use of the agent in cosmetic products [L4873] and in other products where it may
Nefazodone
go.drugbank.com/drugs/DB01149ApprovedWithdrawnOn May 20, 2004, Bristol-Myers Squibb discontinued the sale of Serzone in the United States. … Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with the incidence of severe liver damage was shown to be approximately 1 in 250,000 to
Categories: Antidepressive Agents Indicated for Depression, P-glycoprotein inducersHyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigational[A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties.
Mixtures: UR N-C Urinary Antiseptic, PB HyosCategories: Drugs for Functional Gastrointestinal DisordersDitiocarb zinc
go.drugbank.com/drugs/DB14193ApprovedSensitivity to ditiocarb zinc may be identified with a clinical patch test. … Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen.
Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, Cytochrome P-450 CYP2A6 InhibitorsHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect. … [A189753] Hydroxyzine is also used for generalized anxiety disorder, tension caused by psychoneurosis, and other conditions with manifestations of anxiety.[L9677]
Categories: Histamine Receptor Antagonists, P-glycoprotein substrates