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Displaying results 1781 - 1790 of 2744 in total
  1. Drug

    Gumelutamide

    go.drugbank.com/drugs/DB21615
    Experimental

    The usage of the INN stem '-lutamide' in the name indicates that Gumelutamide is a non-steroid antiandrogen. Gumelutamide has a monoisotopic molecular weight of 420.15 Da.

  2. Drug

    Frevecitinib

    go.drugbank.com/drugs/DB21681
    Investigational

    The usage of the INN stem '-citinib' in the name indicates that Frevecitinib is a Janus kinase inhibitor. Frevecitinib has a monoisotopic molecular weight of 415.18 Da.

  3. Drug

    Odentegravir

    go.drugbank.com/drugs/DB21708
    Experimental

    The usage of the INN stem '-tegravir' in the name indicates that Odentegravir is a HIV integrase inhibitor. Odentegravir has a monoisotopic molecular weight of 421.12 Da.

  4. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

    go.drugbank.com/bio_entities/BE0000037
    TargetHumans

    Essential for the catalytic activity and assembly of complex I (PubMed:22499348) … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-23kD
  5. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

    go.drugbank.com/bio_entities/BE0000093
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-13kD-A
  6. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

    go.drugbank.com/bio_entities/BE0000307
    TargetEnzymeHumans

    Essential for the catalytic activity of complex I (PubMed:17275378) … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-20kD
  7. Drug

    AEM-28

    go.drugbank.com/drugs/DB17642
    Investigational

    AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.[A258764]

    Synonyms: AEM 28, AEM-28
  8. Drug

    Galamustine

    go.drugbank.com/drugs/DB21062
    Experimental

    The usage of the INN stem '-mustine' in the name indicates that Galamustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative.

  9. Drug

    Barucainide

    go.drugbank.com/drugs/DB19585
    Experimental

    The usage of the INN stem '-cain-' in the name indicates that Barucainide is a class I antiarrhythmic, procainamide and lidocaine derivative.

  10. Drug

    Eptazocine

    go.drugbank.com/drugs/DB19670
    Experimental

    The usage of the INN stem '-azocine' in the name indicates that Eptazocine is a narcotic antagonist/agonist related to 6,7-benzomorphan. Eptazocine has a monoisotopic molecular weight of 231.16 Da.