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Displaying results 171 - 180 of 1717 in total
  1. Drug

    Eflepedocokin alfa

    go.drugbank.com/drugs/DB16366
    Investigational

    Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant … region (IgG2-Fc).

    Categories: Proteins, Recombinant ProteinsSynonyms: IL-22 fusion protein, F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO AN IMMUNOGLOBULIN CONSTANT REGION (IGG2-FC))
  2. Drug

    Epoetin beta

    go.drugbank.com/drugs/DB19434
    Investigational

    Synonyms: 1-165-ERYTHROPOIETIN (HUMAN CLONE LHEPOFL13 PROTEIN MOIETY), GLYCOFORM .BETA.Categories: Proteins, Amino Acids, Peptides, and Proteins
  3. Drug

    Efungumab

    go.drugbank.com/drugs/DB16151
    Investigational

    Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).

    Synonyms: Immunoglobulin, anti-(candida heat-shock protein hsp 90) (human monoclonal hsp90mab fragment)Categories: Proteins, Blood Proteins
  4. Drug

    Brenetafusp

    go.drugbank.com/drugs/DB19441
    Investigational

    Brenetafusp is under investigation in clinical trial NCT04262466 (Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors).

    Synonyms: Immunoglobulin, anti-(human CD3 antigen ε-chain) (human-Mus musculus single-chain Fv fragment VL-((GGGGS)4GGGS)-VH) fusion protein with peptide linker (GGGGS) fusion protein with T-cell receptor β chain
  5. Drug

    Evorpacept

    go.drugbank.com/drugs/DB17573
    Investigational

    Evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).

    Categories: Proteins, Blood ProteinsSynonyms: A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain
  6. Drug

    Anti-CD7 CAR T-cell therapy

    go.drugbank.com/drugs/DB18128
    Experimental

    Synonyms: A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7, Anti-CD7 CAR T-cell therapy
  7. Drug

    Viagenpumatucel-L

    go.drugbank.com/drugs/DB16348
    Investigational

    Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).

    Synonyms: Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine, Viagenpumatucel l
  8. Drug

    Letolizumab

    go.drugbank.com/drugs/DB19072
    Investigational

    Letolizumab is under investigation in clinical trial NCT02273960 (Study to Evaluate Safety and Efficacy in Adult Subjects With ITP).

    Synonyms: Immunoglobulin (synthetic light chain variable region fragment) fusion protein with immunoglobulin g (synthetic fc fragment), noncovalently linked dimer
  9. Drug

    Ilorasertib

    go.drugbank.com/drugs/DB11694
    Investigational

    Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.

    Synonyms: 1-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea, 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl)urea)Categories: Protein Kinase Inhibitors, Heterocyclic Compounds, 1-Ring
  10. Drug

    CVac

    go.drugbank.com/drugs/DB17351
    Experimental

    Synonyms: Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase) coupled to oxidized polymannose