Search

Displaying results 171 - 180 of 2506 in total
  1. Drug

    Mitapivat

    go.drugbank.com/drugs/DB16236
    ApprovedInvestigational

    [A245478] On February 17, 2022, the FDA approved mitapivat as the first disease-modifying treatment for hemolytic anemia in adults with pyruvate kinase (PK) deficiency, a rare, inherited disorder leading

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A2 Substrates
  2. Drug

    Oxyquinoline

    go.drugbank.com/drugs/DB11145
    ApprovedInvestigationalVet approved

    Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.

    Mixtures: Fem pH
  3. Drug

    Albuterol

    go.drugbank.com/drugs/DB01001
    ApprovedInvestigationalVet approved

    Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity fo...

    Mixtures: Besmate Inhalation Solution Unit dose PE Bottles 2.5mlCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  4. Indication

    Generalized Convulsive Epilepsy

    go.drugbank.com/conditions/DBCOND0031733
    Drugs: Valpromide
    Synonyms: Tonic-clonic seizure, Tonic-clonic seizures
  5. Drug

    Baloxavir marboxil

    go.drugbank.com/drugs/DB13997
    ApprovedInvestigational

    Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation. It is a prodrug of baloxavir with an impro...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  6. Drug

    Nirmatrelvir

    go.drugbank.com/drugs/DB16691
    ApprovedInvestigational

    [A234224,A234229,A234234] In 2020, Pfizer was investigating another potential treatment for SARS-CoV-2, [PF-07304814]. … Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CL<sup>PRO</sup>) inhibitor that is the subject of clinical trial NCT04756531.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  7. Indication

    Angle-Closure Glaucoma

    go.drugbank.com/conditions/DBCOND0041713
    Drugs: Pilocarpine
    Synonyms: Glaucoma, Closed-Angle, Closed-angle glaucoma
  8. Drug

    Mifamurtide

    go.drugbank.com/drugs/DB13615
    ApprovedInvestigational

    Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). … The overall result of MDP recognition leads to the production of proinflammatory cytokines and promotion of bactericidal and tumoricidal effects [A31745].

  9. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    Tramadol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine. Due to its good tolerability profile and multimodal mechanism of actio...

    Mixtures: DUODUET - PT, AUROMYOTRAM-P ® TABLETASCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Indication

    Partial Seizures With Secondary Generalization

    go.drugbank.com/conditions/DBCOND0061516
    Drugs: Carbamazepine
    Synonyms: Focal to bilateral tonic-clonic seizure, FBTCS - focal to bilateral tonic-clonic seizure