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Ceftazidime
go.drugbank.com/drugs/DB00438ApprovedInvestigationalBacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibio...
Mixtures: CEFAZIME FOR INJECTION 1 g/vialProducts: Ceptaz Inj 1gm/vial, Ceptaz Inj 2gm/vialAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Mixtures: FROSDEM-P, XL-3 VRInternational brands: PK-MerzCefepime
go.drugbank.com/drugs/DB01413ApprovedInvestigationalThe activity of cefepime against Enterobacteriaceae, _Pseudomonas aeruginosa_, and _Staphylococcus aureus_ is due to its high stability toward beta-lactamases. … [A249050] The popularity of its third-generation predecessors, its clinical efficacy, and the high prevalence of multidrug-resistant bacteria might be some of the factors leading to an increase in the
Products: CEFEPIMA 1G/VIAL, VERAPIME Powder for Injection 1g/vialRemdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigationalLike other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase (RdRp) enzyme complex for genomic replication, which can be inhibited by a class of drugs known as nucleoside analogues. … [A222398] Remdesivir (GS-5734) is an adenosine triphosphate analogue first described in the literature in 2016 as a potential treatment for Ebola.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL), VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIALTigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalTigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was gra...
Synonyms: (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamideProducts: TIGECLIN® 50 MG VIAL, TYGACIL INYECTABLE 50 MG VIALCefotaxime
go.drugbank.com/drugs/DB00493ApprovedInvestigationalCefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to c...
Products: CEFOTAXIMA DR. REDDY'S, Claforan 1gm/vialCamphor
go.drugbank.com/drugs/DB01744ApprovedInvestigationalWithdrawnIt is used topically as a skin antipruritic and as an anti-infective agent. … [A254252,L43942] However, camphor can be found in several nonprescription medications at lower concentrations.[A254252]
Mixtures: Chapstick Medicated Lip Balm - Jar, POMADA VILASynonyms: D-Camphor, Camphor(D)Decitabine
go.drugbank.com/drugs/DB01262ApprovedInvestigational[L14962] It is also available as an oral combination product together with the cytidine deaminase inhibitor [cedazuridine]. … Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.
Synonyms: 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-oneProducts: DECI SPAL-P 50 Decitabine Powder for Concentrate for Solution for Infusion, 50 mg/vial, DECI SPAL-P 50Progesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedA low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].
Mixtures: Estradiol and ProgesteroneCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsInterferon alfa-2b
go.drugbank.com/drugs/DB00105ApprovedInvestigationalIt is used extensively as an antiviral or antineoplastic agent.
Mixtures: Intron A - Kit (pws+diluent) 3000000iu/vial, Intron A - Kit (pws+diluent) 5000000iu/vialCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors