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AOC 1001
go.drugbank.com/drugs/DB18620InvestigationalDelpacibart (AOC 1001) is being investigated in a global study for the treatment of Myotonic Dystrophy type 1 (DM1) in clinical trial NCT06411288
Synonyms: Immunoglobulin G1 [233-alanine,234-alanine,327-arginine,de-446-lysine], anti-(human type 1 transferrin receptor) (human-Mus musculus clone AV05 γ1-chain), disulfide with human-Mus musculus clone AV05 κ-chainAlminoprofen
go.drugbank.com/drugs/DB13314ExperimentalAlminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
Synonyms: 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propionic acidHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.
Mixtures: ATARAX FILM TABLET, 30 ADET, ATARAX FILM TABLET, 30 ADETProducts: Atarax, ATARAXPaclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedUsed as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel … Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others.
Synonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine, Taxol ACategories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexAKV-9
go.drugbank.com/drugs/DB18061ExperimentalSynonyms: 5-((S)-1-(3,5-bis(trifluoromethyl)phenoxy)ethyl)-3-hydroxycyclohex-2-en-1-oneBarzolvolimab
go.drugbank.com/drugs/DB18934InvestigationalBarzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Synonyms: Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-MusLarsucosterol
go.drugbank.com/drugs/DB18079InvestigationalSynonyms: 25-hydroxycholest-5-en-3.beta.-yl hydrogen sulfate, Cholest-5-ene-3,25-diol, 3-(hydrogen sulfate), (3.beta.)-Timbetasin
go.drugbank.com/drugs/DB19119InvestigationalTimbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).
Synonyms: 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)thymosin .beta.4(human), Thymosin .beta.(4), 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)-Zetomipzomib
go.drugbank.com/drugs/DB16070InvestigationalZetomipzomib is under investigation in clinical trial NCT04033926 (A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis).
Synonyms: (2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamideRivanicline
go.drugbank.com/drugs/DB05855ExperimentalRivanicline (TC-2403, RJR-2403, (E)-metanicotine) is a partial agonist at neuronal nicotinic acetylcholine receptors, binding primarily to the α4β2 subtype. … Rivanicline also has stimulant and analgesic actions which are thought due to increased noradrenaline release.
Synonyms: (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine, (E)-metanicotine