This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Alminoprofen
DrugBank Accession Number
DB13314
Background

Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 219.284
Monoisotopic: 219.125928791
Chemical Formula
C13H17NO2
Synonyms
  • 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propionic acid
  • Alminoprofen
  • alminoprofene
  • alminoprofeno
  • alminoprofenum
  • p-((2-Methylallyl)amino)hydratropic acid
  • α-methyl-4-[(2-methyl-2-propenyl)amino]benzeneacetic acid
External IDs
  • EB 382
  • EB-382

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbacavirAlminoprofen may decrease the excretion rate of Abacavir which could result in a higher serum level.
AbciximabThe risk or severity of bleeding and hemorrhage can be increased when Alminoprofen is combined with Abciximab.
AcebutololAlminoprofen may decrease the antihypertensive activities of Acebutolol.
AceclofenacThe risk or severity of adverse effects can be increased when Aceclofenac is combined with Alminoprofen.
AcemetacinThe risk or severity of adverse effects can be increased when Alminoprofen is combined with Acemetacin.
AcenocoumarolThe risk or severity of bleeding and hemorrhage can be increased when Alminoprofen is combined with Acenocoumarol.
AcetaminophenThe risk or severity of adverse effects can be increased when Acetaminophen is combined with Alminoprofen.
AcetohexamideThe protein binding of Acetohexamide can be decreased when combined with Alminoprofen.
Acetylsalicylic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Alminoprofen.
AclidiniumAlminoprofen may decrease the excretion rate of Aclidinium which could result in a higher serum level.
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Food Interactions
Not Available

Products

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International/Other Brands
Minalfen

Categories

ATC Codes
M01AE16 — Alminoprofen
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as phenylpropanoic acids. These are compounds with a structure containing a benzene ring conjugated to a propanoic acid.
Kingdom
Organic compounds
Super Class
Phenylpropanoids and polyketides
Class
Phenylpropanoic acids
Sub Class
Not Available
Direct Parent
Phenylpropanoic acids
Alternative Parents
Phenylalkylamines / Aniline and substituted anilines / Secondary alkylarylamines / Amino acids / Monocarboxylic acids and derivatives / Carboxylic acids / Organopnictogen compounds / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds
Substituents
2-phenylpropanoic-acid / Amine / Amino acid / Amino acid or derivatives / Aniline or substituted anilines / Aromatic homomonocyclic compound / Benzenoid / Carbonyl group / Carboxylic acid / Carboxylic acid derivative
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
substituted aniline, monocarboxylic acid, secondary amino compound, amino acid (CHEBI:31190)
Affected organisms
Not Available

Chemical Identifiers

UNII
0255AHR9GJ
CAS number
39718-89-3
InChI Key
FPHLBGOJWPEVME-UHFFFAOYSA-N
InChI
InChI=1S/C13H17NO2/c1-9(2)8-14-12-6-4-11(5-7-12)10(3)13(15)16/h4-7,10,14H,1,8H2,2-3H3,(H,15,16)
IUPAC Name
2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propanoic acid
SMILES
CC(C(O)=O)C1=CC=C(NCC(C)=C)C=C1

References

General References
Not Available
KEGG Drug
D01513
ChemSpider
2013
RxNav
17387
ChEBI
31190
ChEMBL
CHEMBL1765293
Wikipedia
Alminoprofen

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.676 mg/mLALOGPS
logP0.47ALOGPS
logP1.86ChemAxon
logS-2.5ALOGPS
pKa (Strongest Acidic)4.15ChemAxon
pKa (Strongest Basic)4.77ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area49.33 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity65.58 m3·mol-1ChemAxon
Polarizability24.78 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created at June 23, 2017 20:39 / Updated at February 21, 2021 18:54