This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Alminoprofen
- DrugBank Accession Number
- DB13314
- Background
Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Alminoprofen (DB13314)
- Weight
- Average: 219.284
Monoisotopic: 219.125928791 - Chemical Formula
- C13H17NO2
- Synonyms
- 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propionic acid
- Alminoprofen
- alminoprofene
- alminoprofeno
- alminoprofenum
- p-((2-Methylallyl)amino)hydratropic acid
- α-methyl-4-[(2-methyl-2-propenyl)amino]benzeneacetic acid
- External IDs
- EB 382
- EB-382
Pharmacology
- Indication
Not Available
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Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbacavir Alminoprofen may decrease the excretion rate of Abacavir which could result in a higher serum level. Abciximab The risk or severity of bleeding and hemorrhage can be increased when Alminoprofen is combined with Abciximab. Acebutolol Alminoprofen may decrease the antihypertensive activities of Acebutolol. Aceclofenac The risk or severity of adverse effects can be increased when Aceclofenac is combined with Alminoprofen. Acemetacin The risk or severity of adverse effects can be increased when Alminoprofen is combined with Acemetacin. Acenocoumarol The risk or severity of bleeding and hemorrhage can be increased when Alminoprofen is combined with Acenocoumarol. Acetaminophen The risk or severity of adverse effects can be increased when Acetaminophen is combined with Alminoprofen. Acetohexamide The protein binding of Acetohexamide can be decreased when combined with Alminoprofen. Acetylsalicylic acid The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Alminoprofen. Aclidinium Alminoprofen may decrease the excretion rate of Aclidinium which could result in a higher serum level. 
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- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- International/Other Brands
- Minalfen
Categories
- ATC Codes
- M01AE16 — Alminoprofen
- Drug Categories
- Acids, Acyclic
- Agents causing hyperkalemia
- Agents that produce hypertension
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antiinflammatory and Antirheumatic Products
- Antiinflammatory and Antirheumatic Products, Non-Steroids
- Antirheumatic Agents
- Fatty Acids
- Fatty Acids, Volatile
- Lipids
- Musculo-Skeletal System
- Nephrotoxic agents
- Non COX-2 selective NSAIDS
- Peripheral Nervous System Agents
- Propionates
- Sensory System Agents
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as phenylpropanoic acids. These are compounds with a structure containing a benzene ring conjugated to a propanoic acid.
- Kingdom
- Organic compounds
- Super Class
- Phenylpropanoids and polyketides
- Class
- Phenylpropanoic acids
- Sub Class
- Not Available
- Direct Parent
- Phenylpropanoic acids
- Alternative Parents
- Phenylalkylamines / Aniline and substituted anilines / Secondary alkylarylamines / Amino acids / Monocarboxylic acids and derivatives / Carboxylic acids / Organopnictogen compounds / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds
- Substituents
- 2-phenylpropanoic-acid / Amine / Amino acid / Amino acid or derivatives / Aniline or substituted anilines / Aromatic homomonocyclic compound / Benzenoid / Carbonyl group / Carboxylic acid / Carboxylic acid derivative
- Molecular Framework
- Aromatic homomonocyclic compounds
- External Descriptors
- substituted aniline, monocarboxylic acid, secondary amino compound, amino acid (CHEBI:31190)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0255AHR9GJ
- CAS number
- 39718-89-3
- InChI Key
- FPHLBGOJWPEVME-UHFFFAOYSA-N
- InChI
- InChI=1S/C13H17NO2/c1-9(2)8-14-12-6-4-11(5-7-12)10(3)13(15)16/h4-7,10,14H,1,8H2,2-3H3,(H,15,16)
- IUPAC Name
- 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propanoic acid
- SMILES
- CC(C(O)=O)C1=CC=C(NCC(C)=C)C=C1
References
- General References
- Not Available
- External Links
- KEGG Drug
- D01513
- ChemSpider
- 2013
- 17387
- ChEBI
- 31190
- ChEMBL
- CHEMBL1765293
- Wikipedia
- Alminoprofen
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.676 mg/mL ALOGPS logP 0.47 ALOGPS logP 1.86 Chemaxon logS -2.5 ALOGPS pKa (Strongest Acidic) 4.15 Chemaxon pKa (Strongest Basic) 4.77 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 49.33 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 65.58 m3·mol-1 Chemaxon Polarizability 24.78 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at June 23, 2017 20:39 / Updated at February 21, 2021 18:54