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Gentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approvedwhich may limit its use. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity
International brands: G-Mycin, U-gencinMixtures: DIFAZIN MAX ®., PHI KANG YANGSodium fluorophosphate
go.drugbank.com/drugs/DB09484ApprovedInvestigationalSodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Mixtures: Dr. DADDYS Kids Tooth, Dr. DADDYS GumToothpasteCategories: Compounds used in a research, industrial, or household settingSesame oil
go.drugbank.com/drugs/DB11172ApprovedNutraceuticalSesame oil is considered an indirect additive used in food cotact substances by the FDA. … Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices.
Synonyms: Zhi ma oil, Zhi ma youMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigationalIt demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.[A180826] … [A180805] This drug is an immunosuppressant combined with drugs such as [Cyclosporine] and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoateCyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approvedCyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions.
Synonyms: Cyclosporin A, Cyclosporine ACategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexFluconazole
go.drugbank.com/drugs/DB00196ApprovedInvestigationalFluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. … This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole].
Mixtures: Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4%, KADMIZOL®-FCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsPancrelipase
go.drugbank.com/drugs/DB00085ApprovedInvestigationalPancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.
Mixtures: Alka-pan Tablets, FLATOL®Products: CREON® CAPSULAS DE LIBERACION RETARADADA 10.000, PANZYTRAT OK MA RE MICROTATolcapone
go.drugbank.com/drugs/DB00323ApprovedInvestigationalWithdrawnTolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. … It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone, 3,4-dihydroxy-5-nitro-4'-methylbenzophenonePyrantel
go.drugbank.com/drugs/DB11156ApprovedVet approvedPyrantel was initially described in 1965 by researchers from Pfizer who sought cyclic amidines with suitable pharmacokinetic properties (specifically, duration of action) for use as an anthelmintic drug … Pyrantel is mainly available in formulations for dogs and cats as the embonate salt, containing a 34.7% pyrantel base [L1900].
Mixtures: PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN., PAMOATO DE OXANTEL 250 MG/5ML + PAMOATO DE PIRANTEL 250 MG/5 ML SUSPENSIÓN.Categories: Heterocyclic Compounds, 1-RingDienogest
go.drugbank.com/drugs/DB09123ApprovedInvestigationalDienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. … In Europe, Australia, Malaysia, Singapore and Japan, dienogest single therapy is an approved treatment for endometriosis to alleviate painful symptoms of endometriosis and reduce endometriotic lesions
Mixtures: Foxinette 0,03 mg/2 mg 21+7 - Filmtabletten, Velbienne 1 mg/2 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates