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Colistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalIt is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: APSASOL COLISTIN Powder 100 mg/g, Colit 150 MIU Water Soluble PowderAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … [A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality
Mixtures: TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET, TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesButylscopolamine
go.drugbank.com/drugs/DB09300ApprovedInvestigationalVet approvedButylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent. … It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.
Mixtures: TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 40 ADET, TRANKO-BUSKAS 10 MG + 10 MG KAPLI TABLET, 20 ADETProducts: BUTYLSCOPOLAMIN CA 20MG/ML, BUSCOPAN 10 MG KAPLI TABLET, 50 ADETRoxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalRoxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Ernevod 150 mg Film Kaplı Tablet (12 adet), EVRENZO 150 MG FİLM KAPLI TABLET, 12 ADETLipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Mixtures: PIO-ALA 15/600 MG FILM KAPLI TABLET ,30 ADET, PIO-ALA 15/600 MG FILM KAPLI TABLET ,90 ADETCategories: Compounds used in a research, industrial, or household settingIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39076] On the available products, ibuprofen is administered as a racemic mixture. … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.
Mixtures: COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML, Combogesic 500 mg/150 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMeloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approvedIt is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201] … [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations.
Mixtures: OCAM PROTECT 15 MG, OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAmprenavir
go.drugbank.com/drugs/DB00701ApprovedWithdrawnAmprenavir is a protease inhibitor used to treat HIV infection.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: AGENERASE®CAPSULA 150 MG, AGENERASE ® SOLUCION ORAL 15 MG/ML.Pirfenidone
go.drugbank.com/drugs/DB04951ApprovedInvestigationalPirfenidone is a synthetic pyridone drug. … [A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that is used to treat idiopathic pulmonary fibrosis (IPF),[L26801] which is a chronic, progressive form
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: KITOSCELL LP, ESBRİET 267 MG FİLM KAPLI TABLET, 180Benzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalMoreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base. … Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties
Mixtures: TANTUM VERDE DUO 22,5 MG+18 MG/15 ML GARGARA, TANTUM VERDE DUO FORTE 45 MG+18 MG/15 ML GARGARAProducts: DIFFLAM SOLUTION 22.5 mg/15 ml, TANFLEX FORT %0.30 ORAL SPREY, ÇÖZELTİ, 15 ML