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Carbamazepine
go.drugbank.com/drugs/DB00564ApprovedInvestigationalCarbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexProducts: TIMONIL 150 RETARD, Nu-carbamazepine Tab 200mgCefaclor
go.drugbank.com/drugs/DB00833ApprovedInvestigationalSemisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Synonyms: 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acidMixtures: SEFKLAV 250/62.5 MG EFERVESAN TABLET, 20 ADET, SEFKLAV 500/125 MG EFERVESAN TABLET, 20 ADETTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceuticalTretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol). … [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism.
Synonyms: Tretin M, Vitamin A acidInternational brands: Stieva-AAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D]. … The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback mechanism regulates the final activation step of vitamin D in the kidneys.
Categories: Vitamin D and AnaloguesSynonyms: 1α-hydroxyvitamin D3, 1α-hydroxy-vitamin D3Irbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigational[L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy. … Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.
Mixtures: IRBESARTAN COM PU 150/12.5, IRBESARTAN COM PU 150/12.5Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: DU-TWO ® 30 MG, DU-TWO ® 60 MGLansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigationalLansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. … [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)
Mixtures: LACOMBI 15/10 MG KAPSUL, 28 ADET, DUOLANS 15/30 MG SR KAPSUL, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C18 SubstratesNitrendipine
go.drugbank.com/drugs/DB01054ApprovedWithdrawnNitrendipine is a calcium channel blocker with marked vasodilator action. … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Mixtures: Baroprine 10 mg/20 mg Tabletten, Cenipres 10 mg/20 mg TablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesOlanzapine
go.drugbank.com/drugs/DB00334ApprovedInvestigationalOlanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent. … The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to
Mixtures: TARGET 6 MG /50 MG KAPSUL, 90 ADET, TARGET 6 MG /50 MG KAPSUL, 30 ADETCategories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedAs well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094]. … well as athlete's foot [A174097].
Mixtures: Imazol duo 10 mg/g + 2,5 mg/g Creme, SAEROGENTA-A CREAMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers