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Displaying results 171 - 180 of 10000 in total
  1. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep.

    Synonyms: Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers
  2. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. … Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection.

    Mixtures: Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  3. Drug

    Rocuronium

    go.drugbank.com/drugs/DB00728
    ApprovedInvestigational

    [Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium. … The drug is associated with the risk of developing allergic reactions in some high-risk patients, such as those with asthma.

    Products: ANTARİN 100 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET, JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ ,10 FLAKON
  4. Drug

    Amoxicillin

    go.drugbank.com/drugs/DB01060
    ApprovedInvestigationalVet approved

    Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. … [A190648] Amoxicillin was granted FDA approval on 18 January 1974.[L11644]

    Mixtures: AMOXICLAV BASI 500MG/125MG, AMOXICLAV BASI 500MG/125MGCategories: Penicillin G, Cytochrome P-450 CYP2C8 Inhibitors
  5. Drug

    Levothyroxine

    go.drugbank.com/drugs/DB00451
    ApprovedInvestigational

    Stimulating Hormone (TSH) release by the pituitary gland, a normally functioning thyroid gland will produce and secrete T<sub>4</sub>, which is then converted through deiodination (by type I or type II 5′ … [A179935] As a result, many cardiac functions including heart rate, cardiac output, and systemic vascular resistance are closely linked to thyroid status.

    Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, SYNTHROID® 112 MCG TABLETASCategories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  6. Drug

    Iopamidol

    go.drugbank.com/drugs/DB08947
    ApprovedInvestigational

    Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.

    Products: PAMIRAY 370 ENJ. 50 ML 0,755 MG FLAKON, 1 ADET, PAMİRAY 300 MG/ML IV/İNTRAARTİKÜLER/İNTRATEKAL ENJEKSİYONLUK ÇÖZELTİ (50 ML)
  7. Drug

    Valproic acid

    go.drugbank.com/drugs/DB00313
    ApprovedInvestigational

    [L6190] Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects. … [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century.

    Mixtures: PROKSIVAL XR 500 MG UZUN ETKILI FILM TABLET, 50 ADET, PROKSIVAL XR 500 MG UZUN ETKILI FILM TABLET, 50 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  8. Drug

    Mevonlerbart

    go.drugbank.com/drugs/DB19416
    Investigational

    Mevonlerbart is under investigation in clinical trial NCT06602726 (A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat Allergy).

    Synonyms: gamma4 heavy chain Homo sapiens (1-442) [VH (Homo sapiens IGHV3-23*04 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92
  9. Drug

    Naproxen

    go.drugbank.com/drugs/DB00788
    ApprovedInvestigationalVet approved

    [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. … Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994.

    Mixtures: TIYOKSEN 550 MG/8 MG FILM TABLET,10 ADET, APRANAX PLUS 550 MG/30 MG FILM KAPLI TABLET, 10 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  10. Drug

    Indomethacin

    go.drugbank.com/drugs/DB00328
    ApprovedInvestigational

    Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] … [A177871] Since then, indometacin has been extensively studied in clinical trials as one of the most potent NSAIDs in blocking prostaglandin synthesis and was among the first NSAIDs to be used in the symptomatic

    Synonyms: 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acidMixtures: INDOBIOTIC GOZ DAMLASI, 5 ML