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Tocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigationalTocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. … [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies.
Categories: Interleukin-6 Receptor AntagonistProducts: ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE), ACTEMRA 162MG/0.9ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGELevocarnitine
go.drugbank.com/drugs/DB00583ApprovedInvestigationalIt is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Products: ALMİBA 1G/5 ML İM/IV ENJEKSİYONLUK ÇÖZELTİ,5 ADET, ALMİBA 1G/5 ML İM/IV ENJEKSİYONLUK ÇÖZELTİ,10 ADETSulbactam
go.drugbank.com/drugs/DB09324ApprovedInvestigational[L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296] … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.
Mixtures: SULPERAZON 1G IM/IV, UNASYN IM/IV 1.5GProducts: B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 5 ADET, B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 100 ADETGadobenic acid
go.drugbank.com/drugs/DB00743ApprovedInvestigational[A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the biliary system, it is a useful contrast agent for liver MRI. … [A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity.
Categories: Compounds used in a research, industrial, or household settingProducts: MULTIHANCE TEK DOZLUK IV ENJEKSIYONLUK COZELTI ICEREN FLAKON, 5 ML, MultiHance 0,5 mmol/ml Injektionslösung in einer FertigspritzeHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnIn Asia, infection often occurs early in life, leading to a hepatitis B marker prevalence of more than 70% in the general population and a carrier rate of up to 20%. … Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada.
Mixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 10 ADETProducts: ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML, ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 10mcg/0.5mlSodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. … Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.
Mixtures: Potassium Chloride In Sodium Chloride Injection USP, Dextrose 2.5% In Half Strength Lactated Ringer's Injection, USPProducts: Na-zone, Sodium Chloride Inj 0.9% USPVitamin A
go.drugbank.com/drugs/DB00162ApprovedInvestigationalNutraceuticalVet approvedRetinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the … Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Mixtures: Cod Liver Oil USP, Adeks - DpsCategories: Retinoids for Topical Use in Acne, Compounds used in a research, industrial, or household settingButylscopolamine
go.drugbank.com/drugs/DB09300ApprovedInvestigationalVet approvedIt is used to treat pain and discomfort caused by abdominal cramps, menstrual cramps, or other spasmodic activity in the digestive system. It is also effective at preventing bladder spasms. … It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and spasms from occurring.
Products: HİYOSPAZM 20 MG/ML İM/İV/SC ENJEKSİYONLUK ÇÖZELTİ, GİBURİN 20 MG/ML IM/IV/SC ENJEKSİYONLUK ÇÖZELTİ, 6 ADETGolimumab
go.drugbank.com/drugs/DB06674ApprovedInvestigationalThus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate … In the U.S. and Canada, golimumab is marketed under the brand name Simponi®. The FDA label includes a black box warning of serious infections and malignancy.
Categories: Tumor Necrosis Factor Receptor Blocking ActivityProducts: SIMPONI® IV, SIMPONI IVInterferon alfa-2a
go.drugbank.com/drugs/DB00034ApprovedInvestigationalWithdrawnIt is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences. … A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes.
Categories: Interferon Type IProducts: Roferon-A Sol Inj 3million Iu/vial, Roferon-A Soln-liq Im Sc 9million I.U./ml