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Displaying results 171 - 180 of 10000 in total
  1. Drug

    Valproic acid

    go.drugbank.com/drugs/DB00313
    ApprovedInvestigational

    [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … It is currently a compound of interest in the field of oncology for its anti-proliferative effects and is the subject of many clinical trials in a variety of cancer types.

    Mixtures: Depakine Chronosphere 50 mg Retardgranulat in Beuteln, Depakine Chronosphere 50 mg Retardgranulat in BeutelnCategories: UGT1A1 Substrates with a Narrow Therapeutic Index, UGT1A3 Substrates with a Narrow Therapeutic Index
  2. Drug

    Piperacillin

    go.drugbank.com/drugs/DB00319
    ApprovedInvestigational

    It is also used in combination with other antibiotics.

    Mixtures: KABICTAM® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, PIPERACILINA 4G + TAZOBACTAM 0.5G POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLEProducts: PIPERACILLINA EG, TAZOCIN EF 4,5 G IV INFUZYON LIYOFILIZE TOZ ICEREN FLAKON, 1ADET
  3. Drug

    Hepatitis B immune globulin

    go.drugbank.com/drugs/DB05276
    ApprovedInvestigational

    During the process, viruses are deactivated, and in the final steps, solvents used in the preparation are removed. The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. … Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B.

    Products: HEPATECT®CP 500 UI (INMUNOGLOBULINA HUMANA CONTRA EL VIRUS DE LA HEPATITIS B)., HEPATECT ® CP 2000 U.IX 40ML (INMUNOGLOBULINAHUMANAHIPERINMUNECONTRA EL VIRUS DE LA HEPATITIS B)
  4. Drug

    Anidulafungin

    go.drugbank.com/drugs/DB00362
    Approved

    Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. … There is preliminary evidence that it has a similar safety profile to caspofungin.

    Products: GIXOFU 100 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, ANIDULAFUNGINA EG
  5. Drug

    Hyoscyamine

    go.drugbank.com/drugs/DB00424
    ApprovedInvestigational

    Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family. … [A228423] Research into the action of hyoscyamine in published literature dates back to 1826.

    Synonyms: L-Hyoscyamine, L-Tropine tropateMixtures: Uro-L, UR N-C Urinary Antiseptic
  6. Drug

    Carbamazepine

    go.drugbank.com/drugs/DB00564
    ApprovedInvestigational

    It was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. … Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia.

    Categories: UGT2B7 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: Carbamazepine ER, CarbamazepineER ER
  7. Drug

    Octinoxate

    go.drugbank.com/drugs/DB09496
    ApprovedInvestigational

    Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. … It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun.

    Mixtures: Bullet Line, Bullet LineCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Goserelin

    go.drugbank.com/drugs/DB00014
    ApprovedInvestigational

    Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. … In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state.

    Products: Zoladex LA, ZOLADEX LA
  9. Drug

    Phenolphthalein

    go.drugbank.com/drugs/DB04824
    ApprovedWithdrawn

    Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.

    International brands: Feen-a-mint gum, Feen-a-mint laxative mintsMixtures: EX-lax Light Formula Lax W Stool Soften Tab, Lax-BO Tab
  10. Drug

    Formoterol

    go.drugbank.com/drugs/DB00983
    ApprovedInvestigational

    [L11256] It is available as a single-entity product [L10986,L11223] and in several formulations in combination with both inhaled corticosteroids [L10995,L10619] and long-acting muscarinic antagonists. … [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers.

    Mixtures: BUDESONIDE E FORMOTEROLO SANDOZ, BUDESONIDE E FORMOTEROLO SANDOZSynonyms: N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide