Search
Rifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnThe parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid. … [L4800] This drug was also sent for review to the EMA in 2015 by Dr. Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801]
Categories: Antibiotics for Topical Use, Antiinfectives for Systemic UseValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigationalValsartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions. … [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension in adults. Shortly after, in 1997, this drug was approved in the United States.
Synonyms: N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valineMixtures: VALSARTAN COMP PU 160/12.5, VALSARTAN COMP PU 160/12.5Indomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalNSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole … ] The pharmacological effect of indometacin is not fully understood, however, it is thought to be mediated through potent and nonselective inhibition of the enzyme cyclooxygenase (COX), which is the main
Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical UseSynonyms: 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acidTavaborole
go.drugbank.com/drugs/DB09041ApprovedTavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu). … Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseNadofaragene firadenovec
go.drugbank.com/drugs/DB17381ApprovedInvestigational[A255111] Nadofaragene firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and promotes the transduction of IFNα2b. … Most patients with this condition undergo radical cystectomy since other non-surgical treatments are far less effective.
Fenoldopam
go.drugbank.com/drugs/DB00800ApprovedA dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Categories: Antihypertensive Agents Indicated for Hypertension, Dopamine D1 Receptor AgonistsAdenine
go.drugbank.com/drugs/DB00173ApprovedInvestigationalNutraceuticalA purine base and a fundamental unit of adenine nucleotides.
Mixtures: Reveos Select CPD with AS-5 Red Cell Preservative Solution For Collection Of 500ml Of Blood, TERUFLEX Blood Anticoagulant Citrate Phosphate Dextrose Adenine (CPDA-1) for Collection of 450mL of BloodOteseconazole
go.drugbank.com/drugs/DB13055ApprovedInvestigationalOteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51. … [L41635] Unlike previous-generation azole antifungals, oteseconazole has a high selectivity for CYP51 and little interaction with human cytochrome P450s.
Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic UseSodium sulfate
go.drugbank.com/drugs/DB09472ApprovedInvestigationalVet approvedSodium sulfate anhydrous is an electrolyte replenisher and is used in isosmotic solutions so that administration does not disturb normal electrolyte balance and does not lead to absorption or excretion
Mixtures: FORTRANS FOR ORAL SOLUTION, MOVIPREP Pulver zur Herstellung einer Lösung zum EinnehmenCategories: Drugs for ConstipationDoxecitine
go.drugbank.com/drugs/DB02594ApprovedInvestigationalIt is an essential component of the deoxyribonucleotide pool required for DNA synthesis and repair. … This combination is the first and only approved treatment for Thymidine Kinase 2 deficiency.[L54613, L54618]