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Difamilast
go.drugbank.com/drugs/DB14987ApprovedInvestigationalThe drug is indicated for the topical treatment of mild to moderate atopic dermatitis in adults and pediatric patients 2 years of age and older [L55042]. It is approved in Japan and the United States. … [L55042, A275424, A275420] As difamilast's mechanism of action involves the inhibition of PDE4, the inhibition leads to an increase in intracellular cyclic AMP and a subsequent decrease in the production
Iloperidone
go.drugbank.com/drugs/DB04946ApprovedInvestigational[A263547] Iloperidone is currently used to treat schizophrenia and manic or mixed episodes associated with bipolar disorder.[L50527] … [A3024] It is considered to be a second-generation antipsychotic drug [A263552] with multiple receptor binding profile, although it shows high affinity towards 5-HT<sub>2A</sub> and dopamine D2 receptors
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromePine needle oil (pinus mugo)
go.drugbank.com/drugs/DB11276ApprovedPine needle oil is obtained from the needles of Pinus mugo tree via steam distillation. Major components of pine needle oil (pinus mugo) include α-Pinene, β-pinene, δ-3-carene, limonene, β-phellandrene, (E)-caryophyllene, and germacrene ...
Mixtures: Co CoolAzvudine
go.drugbank.com/drugs/DB16407InvestigationalAzvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)).
Phenyltoloxamine
go.drugbank.com/drugs/DB11160ApprovedNevertheless, phenyltoloxamine is used to a fairly limited extent in contemporary medicine, with only very few products involving it as an active ingredient. … Although phenyltoloxamine's ability to potentiate the effects of analgesics may be explained in part by its chemical nature as a first-generation H1 antihistamine that is capable of crossing the blood-brain
Ferric carboxymaltose
go.drugbank.com/drugs/DB08917ApprovedInvestigationalFerric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Vestronidase alfa
go.drugbank.com/drugs/DB12366ApprovedInvestigationalMPS VII is a progressive condition that affects most tissues and organs due to the lack of a lysosomal enzyme called beta-glucuronidase, leading to buildup of toxic metabolites. … Last two conditions are leading causes of fatalities in patients with MPS VII.
Mecobalamin
go.drugbank.com/drugs/DB03614ApprovedInvestigationalSynonyms: Co-methylcobalaminMixtures: Co-Balamin, Co-Veratrol