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Displaying results 1791 - 1800 of 7063 in total
  1. Drug

    Neratinib

    go.drugbank.com/drugs/DB11828
    ApprovedInvestigational

    Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. Approval was granted to Puma Biotechnology Inc. for the tradename Nerlynx. Neratinib i...

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  2. Drug

    Eliglustat

    go.drugbank.com/drugs/DB09039
    ApprovedInvestigational

    Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease. … [L41404,A7634] Eliglustat was approved by the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 Gaucher disease.

  3. Drug

    Ivabradine

    go.drugbank.com/drugs/DB09083
    ApprovedInvestigational

    Ivabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the … Therefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing

    Products: IVABRADIN 1A PHARMA 5MG, IVABRADIN 1A PHARMA 7.5MG
  4. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013.

  5. Drug

    Gilteritinib

    go.drugbank.com/drugs/DB12141
    ApprovedInvestigational

    Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group. … [A40044] Gilteritinib was developed by Astellas Pharma and FDA approved on November 28, 2018.

  6. Drug

    Epinephrine

    go.drugbank.com/drugs/DB00668
    ApprovedInvestigationalVet approved

    Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. … On August 16, 2018, Teva Pharmaceuticals USA gained approval to market its generic epinephrine auto-injector in 0.3 mg and 0.15 mg strengths [L4353].

    Mixtures: D-Care 100X, Ultracaine DS Inj
  7. Drug

    Chlortetracycline

    go.drugbank.com/drugs/DB09093
    ApprovedVet approvedWithdrawn

    He discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained from a soil sample from a field in Missouri. … Chlortetracycline is a _tetracycline_ antibiotic, and historically the first member of this class to be identified.

  8. Drug

    Cefoselis

    go.drugbank.com/drugs/DB19513
    Experimental

    Cefoselis is a small molecule drug. Cefoselis has a monoisotopic molecular weight of 522.11 Da.

  9. Drug

    Elisidepsin

    go.drugbank.com/drugs/DB19522
    Experimental

    Elisidepsin is a small molecule drug. Elisidepsin has a monoisotopic molecular weight of 1476.93 Da.

  10. Drug

    Cargutocin

    go.drugbank.com/drugs/DB19643
    Experimental

    Cargutocin is a small molecule drug. Cargutocin has a monoisotopic molecular weight of 915.48 Da.