Search
Talquetamab
go.drugbank.com/drugs/DB16678ApprovedInvestigationalon July 21, 2023. … [L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and CD3 on T cells.
Synonyms: ANTIBODY; BISPECIFIC GAMMA4 HEAVY CHAIN HUMANIZED AN, IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONALAttapulgite
go.drugbank.com/drugs/DB01574ApprovedVet approvedWithdrawnAttapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. … When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications.
Categories: Compounds used in a research, industrial, or household settingDuvelisib
go.drugbank.com/drugs/DB11952ApprovedInvestigationalAll the work around duvelisib showed that this agent is a potent inhibitor of both forms.[A39025] Duvelisib was developed by Verastem, Inc and FDA approved on September 24, 2018.[L4585] … Duvelisib, also known as IPI-145 and INK-1197, is a small-molecule inhibitor of phosphoinositide-3 kinases that was designed initially to prove that simultaneous inhibition of the isoforms delta and gamma
Bufexamac
go.drugbank.com/drugs/DB13346ApprovedWithdrawnThe use of bufexamac has been discontinued in Canada and the United States, which may be due to undetermined clinical efficacy and a high prevalence of contact sensitization [A32822]. … It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns,
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticSynonyms: 4-Butoxy-N-hydroxybenzeneacetamideMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalThis indication was subsequently expanded to cover EGPA on December 12, 2017, and HES on September 25, 2020.[L16518] … Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline.
Products: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, NUCALA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/MLFrovatriptan
go.drugbank.com/drugs/DB00998ApprovedFrovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. … Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCarprofen
go.drugbank.com/drugs/DB00821ApprovedVet approvedWithdrawnIt is no longer marketed for human usage, after being withdrawn on commercial grounds. … Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs.
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Pulmonary coccidioides
go.drugbank.com/conditions/DBCOND0025124Drugs: ItraconazoleSynonyms: San Joaquin valley feverPhenobarbital
go.drugbank.com/drugs/DB01174ApprovedInvestigationalA barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also i...
Mixtures: Phenaphen No 3 Cap, Phenaphen No 4 CapCategories: combinations of barbiturates, Metabolic Side Effects of Drugs and Substances