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Alpelisib
go.drugbank.com/drugs/DB12015ApprovedInvestigationalIt works by selectively inhibiting class I PI3K p110α [A179203], which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival … Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: PİMREVA 200 MG FİLM KAPLI TABLET, 14 ADET, PİMREVA 200 MG FİLM KAPLI TABLET, 28 ADETZanubrutinib
go.drugbank.com/drugs/DB15035ApprovedInvestigationaltrial whose tumour is entirely or partially destroyed by a drug. … [A187967] BTK is an enzyme that plays a role in oncogenic signalling pathways, promoting the survival and proliferation of malignant B cells.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexProducts: BRUKINSA 80 mg capsulesIocetamic acid
go.drugbank.com/drugs/DB09403ApprovedIocetamic acid is a diagnostic aid (radiopaque medium)
Products: CHOLEBRINE 750 MG (MEDIO DE CONTRASTE RADIOLOGICO)Sacituzumab govitecan
go.drugbank.com/drugs/DB12893ApprovedInvestigationalAs a targeted cytotoxic agent, it is hoped to provide similar efficacy with reduced adverse effects. … [A193653] Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment.
Products: TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADETZinc citrate
go.drugbank.com/drugs/DB11154ApprovedInvestigationalZinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element.
Mixtures: Corvite 150, Vitamin A C E W.niacinam.beta Car.and Min.Products: Zinc 50 mgPefloxacin
go.drugbank.com/drugs/DB00487ApprovedA synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Products: PEMAX TABLET 400 mgApalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalApproximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients show no evidence of cancer metastasis at the time of castration-resistant diagnosis [L1295]. … In a randomized trial, the median metastasis-free survival for patients taking apalutamide was 40.5 months compared to 16.2 months for patients taking a placebo [L1295].
Products: ERLEADA ®TABLETAS RECUBIERTAS 60 MGNeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. … [A175042,A191529] Neomycin A, or [neamine], is a moiety that conjoins two molecules of neomycin B and C together.
Mixtures: THIOCILLINE 500 IU/G + 5 MG/G DERİ MERHEMİ, 30 G, THIOCILLINE 500 IU/G + 5 MG/G GÖZ MERHEMİ, 5 GRCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexAcipimox
go.drugbank.com/drugs/DB09055ApprovedInvestigationalAcipimox is a niacin derivative used as a hypolipidemic agent. … Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL.
Products: OLBETAM CAPSULE 250 mgLenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigational[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral
Products: Sunlenca 300 mg Film Kaplı Tablet (5 Adet)