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Testosterone cypionate
go.drugbank.com/drugs/DB13943ApprovedInvestigationalTestosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and ...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalTestosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. This slow release is achieved by the presence of the enanthate ester functional group attached to the testoste...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesEstradiol cypionate
go.drugbank.com/drugs/DB13954ApprovedVet approvedEstradiol Cypionate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSarracenia Purpurea
go.drugbank.com/drugs/DB13965ApprovedWithdrawnSarracenia purpurea, commonly known as the purple pitcher plant, northern pitcher plant, turtle socks, or side-saddle flower, is a perennial carnivorous plant in the family Sarraceniaceae. Sarracenia purpurea attract and trap insects wit...
Products: P-BlocEchinacea
go.drugbank.com/drugs/DB14240ApprovedInvestigationalCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSaw palmetto
go.drugbank.com/drugs/DB14360ApprovedInvestigationalSaw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme InhibitorsIvosidenib
go.drugbank.com/drugs/DB14568ApprovedInvestigationalIvosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 is an enzyme that is often mutated and overexpressed in some cancers, leading to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1, b...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesEtrasimod
go.drugbank.com/drugs/DB14766ApprovedInvestigationalEtrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that targets the S1P1,4,5 with no detectable activity on S1P2 and S1P3 receptors. S1P receptors are membrane-derived lysophospholipid sig...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesEnsartinib
go.drugbank.com/drugs/DB14860ApprovedInvestigationalNon-small cell lung cancer (NSCLC) is one of the most frequent subtypes of lung cancers and encompasses a variety of different lung cancers, with notable ones being adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. Ensar...
Categories: P-glycoprotein substrates