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Displaying results 1811 - 1820 of 10000 in total
  1. Drug

    Oxerutins

    go.drugbank.com/drugs/DB15826
    Investigational

    Products: Venoruton 500 mg - Tabletten, VENORUTON FORTE 500 MG TABLET, 30 ADET
  2. Drug

    Migalastat

    go.drugbank.com/drugs/DB05018
    ApprovedInvestigational

    [L47036,L47057,L4274,L4278] In the U.S., it is estimated that more than 3,000 people are living with Fabry disease, and an estimated more than 50 percent of these diagnosed patients are currently untreated … [L47036,L47057,L4274,L4278] Globally, it is estimated that approximately 35 to 50 percent of Fabry patients may have amenable GLA variants that are treatable with migalastat.

    Synonyms: (2R,3S,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triolProducts: GALAFOLD 123 MG SERT KAPSÜL, 14 ADET
  3. Drug

    Apalutamide

    go.drugbank.com/drugs/DB11901
    ApprovedInvestigational

    Approximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients show no evidence of cancer metastasis at the time of castration-resistant diagnosis [L1295]. … In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant prostate cancer had ≥50% PSA decline at week 12 of apalutamide treatment [A31846].

    Categories: MATE 2 Inhibitors, Cytochrome P-450 SubstratesProducts: ERLEADA ®TABLETAS RECUBIERTAS 60 MG
  4. Drug

    Prilocaine

    go.drugbank.com/drugs/DB00750
    ApprovedInvestigational

    Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

    Synonyms: N-(2-Methylphenyl)-2-(propylamino)propanamide, alpha-n-Propylamino-2-methylpropionanilideMixtures: LOKARIL % 5 KREM ,10G, R-LATE % 15 + % 5 DERİ SPREYİ, ÇÖZELTİ, 50 ML
  5. Drug

    Primidone

    go.drugbank.com/drugs/DB00794
    ApprovedVet approved

    [L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112] … Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures.

    Synonyms: 2-deoxyphenobarbital, 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dioneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inducers
  6. Drug

    Sulfaquinoxaline

    go.drugbank.com/drugs/DB11464
    ExperimentalVet approved

    Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as

    Products: SN ANTI-COCCI 45 mg/ml ORAL SOLUTION, TP-SQ 250 WSP Sulfaquinoxaline 250 mg/g Powder
  7. Drug

    Regorafenib

    go.drugbank.com/drugs/DB08896
    ApprovedInvestigational

    It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. … Regorafenib is an orally-administered inhibitor of multiple kinases.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsProducts: STIVARGA 40 MG FILM KAPLI TABLET ,84 ADET, STIVARGA 40 MG TABLETA RECUBIERTA
  8. Drug

    Encorafenib

    go.drugbank.com/drugs/DB11718
    ApprovedInvestigational

    [L3344] On June 27, 2018, the Food and Drug Administration approved encorafenib and [binimetinib] (BRAFTOVI and MEKTOVI, Array BioPharma Inc.) in combination for patients with unresectable or metastatic … Mutations in this gene, most frequently the V600E mutation, are the most commonly identified cancer-causing mutations in melanoma, and have been isolated in various other cancers as well, including non-Hodgkin

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: BRAFTOVİ 75 MG SERT KAPSÜL, 42 ADET, BRAFTOVI® 75 MG CÁPSULAS
  9. Drug

    Romiplostim

    go.drugbank.com/drugs/DB05332
    ApprovedInvestigational

    Romiplostim is produced by recombinant DNA technology in Escherichia coli. FDA approved on August 22, 2008. … Each domain consists of 14 amino acids. Interestingly, romiplostim's amino acid sequence is not similar to that of endogenous thrombopoietin.

    Products: NPLATE ® 500 MCG, NPLATE 500 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET
  10. Drug

    Sucralose

    go.drugbank.com/drugs/DB15049
    Investigational

    Sucralose is an artificial sweetener used as a sugar substitute.

    Categories: Compounds used in a research, industrial, or household settingProducts: DE-LİGHT 6.05 MG TABLET, 100 ADET, DE-LİGHT 6.05 MG TABLET, 500 ADET