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Displaying results 1831 - 1840 of 10000 in total
  1. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Pepsin is approved by the FDA and is used in food at levels not to exceed current good manufacturing practice [L2363]. … Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated egg whites to dissolve.

    Mixtures: Neo Life Enzyme Tab, Neo Life Beta Gest Tab
  2. Drug

    Foreskin keratinocyte (neonatal)

    go.drugbank.com/drugs/DB10772
    Approved

    In 1981, O’Conner and his group utilized cultured autologous epithelium to coat burn defects for the first time. … It is used for grafting onto partial-thickness wounds, where it offers a favorable matrix for host cell migration [L2452].

  3. Drug

    Garadacimab

    go.drugbank.com/drugs/DB15629
    Approved

    [A273993] In June 2025, garadacimab was approved by the US FDA for the prophylaxis of HAE episodes in patients ≥12 years of age. … [A273993,A273998] As opposed to [lanadelumab], another prophylactic agent for HAE that targets kallikrein, garadacimab targets activated factor XII, the first factor in the contact system responsible for

    Categories: Drugs Used in Hereditary Angioedema
  4. Drug

    Lanolin

    go.drugbank.com/drugs/DB11112
    Approved

    For this reason, it is also called wool wax or wool grease. Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. … Lanolin is also frequently used in protective baby skin treatment and for sore nipples in breastfeeding mothers [L2583], [A32788].

    Mixtures: Kendra SKIN PROTECTION and PAIN RELIEF FOR HAIR REMOVAL, Skullduggery Pain Relief and Skin Protection for TattoosCategories: Compounds used in a research, industrial, or household setting
  5. Target

    Mitogen-activated protein kinase kinase kinase 19

    go.drugbank.com/bio_entities/BE0009408
    TargetHumans

    Synonyms: Regulated in COPD, protein kinase
  6. Drug

    Trandolapril

    go.drugbank.com/drugs/DB00519
    ApprovedInvestigational

    It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. … for congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.

    Categories: Agents Acting on the Renin-Angiotensin System, Antihypertensive Agents Indicated for Hypertension
  7. Drug

    Voclosporin

    go.drugbank.com/drugs/DB11693
    ApprovedInvestigational

    Early and accurate intervention for LN is important in improving clinical outcomes. … [L31253] In July 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended voclosporin be granted marketing authorization for use in combination with [mycophenolate mofetil]

  8. Drug

    Dutasteride

    go.drugbank.com/drugs/DB01126
    ApprovedInvestigational

    Dutasteride was approved by the FDA in 2001 for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist [tamsulosin] to … However, unlike finasteride, dutasteride is not yet indicated for the treatment of androgenic alopecia although it was demonstrated to be effective in several randomized, double-blind, placebo-controlled

    Categories: Drugs Used in Benign Prostatic HypertrophySynonyms: (5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
  9. Drug

    Fenproporex

    go.drugbank.com/drugs/DB01550
    ApprovedIllicitWithdrawn

    Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. … The N-2-cyanoethyl substituent was once believed to be resistant to cleavage, because fenproporex -- once recommended as an obesity treatment for patients with cardiovascular disease -- was originally

  10. Drug

    Nevirapine

    go.drugbank.com/drugs/DB00238
    ApprovedInvestigational

    A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. … Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.

    Mixtures: ZIMODINE N ®, LAVUZID® NCategories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic Use