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Lenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigational[A228708] Available as oral capsules, lenalidomide is approved by the FDA and EU for the treatment of multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, follicular lymphoma, and marginal
Hypromellose
go.drugbank.com/drugs/DB11075ApprovedInvestigationalHypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water.
Mixtures: Visine for Dry Eye True Tears, Visine for Dry Eye Eye RevivalCategories: Compounds used in a research, industrial, or household settingTrichlormethiazide
go.drugbank.com/drugs/DB01021ApprovedVet approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Haloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigationalHowever, these findings contradict the findings from studies in vitro with human liver microsomes and from drug interaction studies in vivo. … [F4645] It is also used off-label for the management of chorea associated with Huntington's disease and for the treatment of intractable hiccups as it is a potent antiemetic.
Products: HALOPERIDOL MK 5 MG TABLETAS, HALOPERIDOL MK 10 MG TABLETASLesinurad
go.drugbank.com/drugs/DB11560ApprovedWithdrawnIt reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with … Marketed as the product Zurampic, it is indicated for use in combination with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with gout in patients who have not achieved target
Vestronidase alfa
go.drugbank.com/drugs/DB12366ApprovedInvestigationalThe enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as human beta-glucuronidase (GUS) [FDA Label]. … Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line.
Oliceridine
go.drugbank.com/drugs/DB14881ApprovedInvestigational[A218041, A218046] Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which the μ-opioid receptor subtype is predominantly targeted by and is responsible for the effects of … [A218031, A218046] However, due to the ability of some opioid agonists to bind to other targets, as well as activation of additional downstream pathways from opioid receptors such as those involving β-arrestin
Lenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigational[L42995] On December 22, 2022, it was also approved by the FDA.[L44473] … [A244170, A244175, A244180, A244190] Lenacapavir was first globally approved on August 22, 2022 by the European Commission to treat adults with multi-drug resistant HIV infection.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseElexacaftor
go.drugbank.com/drugs/DB15444ApprovedInvestigational[A187361] The triple combination product Trikafta<sup>TM</sup>, manufactured by Vertex Pharmaceuticals, is the first product approved for the treatment of CF in individuals who are either homo- _or_ heterozygous … [A187361] Elexacaftor, along with [VX-659], was designed to fill the need for an efficacious CF therapy for patients who are heterozygous for _F508del-CFTR_ and a gene that does not produce protein or
Monobenzone
go.drugbank.com/drugs/DB00600ApprovedWithdrawnIt exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause destruction of melanocytes and permanent depigmentation. … Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation.