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Phentermine
go.drugbank.com/drugs/DB00191ApprovedIllicitInvestigational[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. … Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.
Risperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] It is one of the most widely used SGAs. [Paliperidone], another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). … Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain.
Products: AS-RISPER 1 MG/ML ORAL COZELTI 100 MLButenafine
go.drugbank.com/drugs/DB01091ApprovedButenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. … In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseMosunetuzumab
go.drugbank.com/drugs/DB15434ApprovedInvestigationalMosunetuzumab is a humanized anti-CD20/CD3 bispecific antibody. … ] and [tisagenlecleucel], it is an “off-the-shelf” alternative, readily available to patients.
Pyridostigmine
go.drugbank.com/drugs/DB00545ApprovedInvestigational[A231004, L32408, L32413] Pyridostigmine is the current drug of choice, with superior pharmacokinetics and reduced side effects compared to [neostigmine]. … [A231004] Acetylcholinesterase inhibitors have been the symptomatic treatment of choice in myasthenia gravis since the 1930s with the early use of [physostigmine] and [neostigmine].
Cabotegravir
go.drugbank.com/drugs/DB11751ApprovedInvestigationalCabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, [rilpivirine].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTannic acid
go.drugbank.com/drugs/DB09372ApprovedInvestigationalTannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. … Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine.
Mecasermin
go.drugbank.com/drugs/DB01277ApprovedInvestigationalThe amino acid sequence of the product is identical to that of endogenous human IGF-1. … The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1.
Categories: Sex Hormones and InsulinsIndomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalIndometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] … [A177871] The pharmacological effect of indometacin is not fully understood, however, it is thought to be mediated through potent and nonselective inhibition of the enzyme cyclooxygenase (COX), which is
Categories: Antiinflammatory Preparations, Non-Steroids for Topical UseDihydroergocristine
go.drugbank.com/drugs/DB13345ApprovedDihydroergocristine is part of the ergoloid mixture products.[L2637] It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline.