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Displaying results 1841 - 1850 of 10000 in total
  1. Drug

    Azilsartan medoxomil

    go.drugbank.com/drugs/DB08822
    ApprovedInvestigational

    Although there is no clinical significance yet determined, azilsartan medoxomil may have potential off-label uses in patients with a history of myocardial infarction or heart failure.[A232863] … As hypertension is a major risk factor for cardiovascular disease,[A7354] early management of hypertension has several implications on patients' survival rate and quality of life in the future.

    Categories: Antihypertensive Agents Indicated for Hypertension, Agents Acting on the Renin-Angiotensin System
  2. Target

    Atypical chemokine receptor 1

    go.drugbank.com/bio_entities/BE0015068
    TargetHumans

    Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. … potential surges in plasma chemokine levels

    Synonyms: Duffy antigen receptor for chemokines
  3. Drug

    Iodide I-131

    go.drugbank.com/drugs/DB09293
    ApprovedInvestigational

    Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. … It is also indicated for use in performance of the radioactive iodide (RAI) uptake test to evaluate thyroid function.

    Salts: Sodium iodide I-131Synonyms: Iodide I-131 ion, Iodide ion I 131
  4. Drug

    Nevirapine

    go.drugbank.com/drugs/DB00238
    ApprovedInvestigational

    A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. … Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.

    Mixtures: ZIMODINE N ®, LAVUZID® NCategories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic Use
  5. Drug

    Dienogest

    go.drugbank.com/drugs/DB09123
    ApprovedInvestigational

    It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself. … In Europe, Australia, Malaysia, Singapore and Japan, dienogest single therapy is an approved treatment for endometriosis to alleviate painful symptoms of endometriosis and reduce endometriotic lesions

    Mixtures: ACOTOL EXCategories: Hormonal Contraceptives for Systemic Use, Contraceptive Agents, Male
  6. Drug

    Adenosine phosphate

    go.drugbank.com/drugs/DB00131
    ApprovedInvestigationalNutraceuticalWithdrawn

    Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937] … Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.

    Synonyms: 5'-O-Phosphonoadenosine
  7. Drug

    Nirmatrelvir

    go.drugbank.com/drugs/DB16691
    ApprovedInvestigational

    [L46921] Paxlovid was approved for use in Canada in January 2022 for the treatment of adult patients with mild-moderate COVID-19 [L39544] and later granted conditional marketing authorization by the European … [L33359] In December 2021, the FDA granted an emergency use authorization to Paxlovid, a co-packaged product containing both nirmatrelvir and [ritonavir], for the treatment of certain patients with

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Acetylcarnitine

    go.drugbank.com/drugs/DB08842
    ApprovedInvestigational

    The main role of acetylcarnitine is to help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs. … Acetylcarnitine can be synthesized, but it is also naturally found in adequate amounts in healthy humans.

    Synonyms: O-Acetylcarnitine, O-acetyl-L-carnitineInternational brands: Memorx IQ Plus
  9. Drug

    Pipradrol

    go.drugbank.com/drugs/DB11584
    ApprovedWithdrawn

    The social and in particular acute clinical harms of pipradrol derivatives have led to their control under the Misuse of Drugs Act 1971 in the UK in 2012 [T178]. … Interestingly, this drug has been studied for bactericidal properties, however, is not currently, used for this purpose [A32725].

    Categories: Psychostimulants, Agents Used for ADHD and Nootropics
  10. Drug

    Zomepirac

    go.drugbank.com/drugs/DB04828
    ApprovedWithdrawn

    The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.

    Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDS