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PF-05241328
go.drugbank.com/drugs/DB15124InvestigationalPF-05241328 is under investigation in clinical trial NCT01165736 (To Calculate the Pharmacokinetics (Concentration of Compound in and Rate of Excretion From the Blood) Following a Very Low Dose of Compound
Methimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigational[A184733] Traditionally, methimazole has been preferentially used over propylthiouracil due to the risk of fulminant hepatotoxicity carried by the latter,[A184757] with propylthiouracil being preferred
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 InhibitorsPoloxamer 188
go.drugbank.com/drugs/DB11333ApprovedDue to its sufactant properties, P188 may also be found in over-the-counter (OTC) products such as toothpaste, laxatives and mouthwash, and used in various cosmetic, industrial and pharmaceutical applications
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsEnalapril
go.drugbank.com/drugs/DB00584ApprovedInvestigationalVet approvedEnalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte ...
Mixtures: ENALAPRIL 1A PL 20/6MG, ENALAPRIL 1A PL 20/6MGCategories: P-glycoprotein inhibitorsOleic Acid
go.drugbank.com/drugs/DB04224ApprovedInvestigationalVet approvedAn unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
Mixtures: NEUROGAIN PB VEGICAP CAPSULE 500MGRanirestat
go.drugbank.com/drugs/DB05327InvestigationalRanirestat is a structurally novel and stereospecifically potent aldose reductase (AKR1B; EC 1.1.1.21) inhibitor, which contains a succinimide ring that undergoes ring-opening at physiological pH levels
Tuparstobart
go.drugbank.com/drugs/DB19118InvestigationalTuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS
Ritlecitinib
go.drugbank.com/drugs/DB14924ApprovedInvestigationalRitlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsBetaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceuticalBetaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell ...
Mixtures: Face It Hd Perfect Bb Spf30 Pa 02, Face It Hd Perfect Bb Spf30 Pa 01