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Pilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigationalA naturally occurring alkaloid derived from the _Pilocarpus_ plants, pilocarpine is a muscarinic acetylcholine agonist.
Mixtures: E-pilo-2 Oph Soln, E-pilo-6 Oph SolnCategories: Cholinergic Receptor Agonist, Cytochrome P-450 SubstratesBrepocitinib
go.drugbank.com/drugs/DB15003ApprovedInvestigationalBrepocitinib is an oral Janus kinase (JAK) and tyrosine kinase 2 (TYK2) inhibitor used to treat dermatomyositis in adults.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsCertolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigational[A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. … Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha).
Categories: Tumor Necrosis Factor Receptor Blocking ActivityProducts: CIMZIA®, CIMZIA 200MG PAT F DOSIERGErythropoietin
go.drugbank.com/drugs/DB00016ApprovedInvestigationalIt has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced. … Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells.
Synonyms: 1-165-Erythropoietin (human clone λHEPOFL13 protein moiety), glycoform αProducts: EPORATIO 20000 I E /1ML, EPORATIO 1000 I E /0.5MLAgmatine
go.drugbank.com/drugs/DB08838ExperimentalAs an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the … Agmantine is a natural metabolite of the amino acid arginine.
Categories: Cytochrome P-450 Substrates, NMDA Receptor AntagonistsSynonyms: 1-amino-4-guanidobutane, N-(4-aminobutyl)guanidineBendroflumethiazide
go.drugbank.com/drugs/DB00436ApprovedInvestigationalA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders.
Mixtures: Corzide Tab W Nadolol 80mg, Corzide Tab W Nadolol 40mgCategories: Heterocyclic Compounds, 2-RingSO-101
go.drugbank.com/drugs/DB05345ExperimentalSO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia. … Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day.
N4-Hydroxycytidine
go.drugbank.com/drugs/DB15660Experimental[A193026] A [remdesivir] resistant mutant mouse hepatitis virus has also been shown to have increased sensitivity to N4-hydroxycytidine. … [A193017] N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses in mice and human airway epithelial cells.
Categories: Heterocyclic Compounds, 1-RingSynonyms: beta-D-N-4-Hydroxycytidine, 4-N-HydroxycytidinePBI-1402
go.drugbank.com/drugs/DB05480ExperimentalSince it stimulates immune activity, it has been considered as a candidate for cancer treatment as well as anemia. … PBI-1402 has a dual therapeutic action; as a chemoprotectant and hematopoietic progenitor stimulator.
AV608
go.drugbank.com/drugs/DB05072InvestigationalAV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).