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Displaying results 181 - 190 of 9987 in total
  1. Drug

    Tetracaine

    go.drugbank.com/drugs/DB09085
    ApprovedInvestigationalVet approved

    Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

    Salts: Tetracaine hydrochlorideMixtures: Lidocaine and Tetracaine, Lidocaine and Tetracaine
  2. Drug

    PRGN-3006

    go.drugbank.com/drugs/DB17229
    Investigational

    PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface

    Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surface
  3. Drug

    Triprolidine

    go.drugbank.com/drugs/DB00427
    Approved

    First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.

    Salts: Triprolidine hydrochloride, Triprolidine hydrochloride monohydrateMixtures: A-FERIN SINUS 500/30/1.25 MG FİLM KAPLI TABLET, 20 ADET, PEACEF SYRUP 30 mg/5 ml
  4. Drug

    Esmolol

    go.drugbank.com/drugs/DB00187
    ApprovedInvestigationalWithdrawn

    The FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride that supply 250 milligrams/milliliter of concentrated esmolol per 10-milliliter ampule … Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine.

    Salts: Esmolol hydrochlorideProducts: Esmolol Hydrochloride, Esmolol Hydrochloride in Water
  5. Drug

    STRO-001

    go.drugbank.com/drugs/DB17224
    Investigational

    Synonyms: antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable maytansinoid linker warheads
  6. Drug

    Surovatamig

    go.drugbank.com/drugs/DB19420
    Investigational

    TNB-486 is under investigation in clinical trial NCT06564038 (A Study of AZD0486 Monotherapy or in Combination With Other Anti-cancer Agents for Mature B-cell Malignancies).

    Synonyms: sapiens and humanized monoclonal antibody asymetric,, immunoglobulin (H-gamma4_L-kappa)_VH-G4(h-CH2-CH3), anti-[Homo sapiens CD3D (CD3 delta) and CD3E (CD3 epsilon, Leu-4) dimer] and anti-[Homo sapiens CD19 (B lymphocyte surface antigen B4, Leu-12)], Homo
  7. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation. … It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

    Salts: Ondansetron hydrochloride, Ondansetron hydrochloride dihydrateCategories: Antiemetics and Antinauseants
  8. Drug

    Topotecan

    go.drugbank.com/drugs/DB01030
    ApprovedInvestigational

    An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.

    Salts: Topotecan hydrochlorideCategories: Antineoplastic and Immunomodulating Agents
  9. Drug

    Ginsenoside Rd

    go.drugbank.com/drugs/DB19256
    Investigational

    Ginsenoside Rd is under investigation in clinical trial NCT00815763 (Efficacy and Safety of Ginsenoside-rd for Acute Ischemic Stroke).

    Synonyms: Ginsenoside Rd (constituent of american ginseng, asian ginseng, and tienchi ginseng), .)-20-(.beta.-d-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl-
  10. Drug

    Cocaine

    go.drugbank.com/drugs/DB00907
    ApprovedIllicitInvestigational

    It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. … An alkaloid ester extracted from the leaves of plants including coca.

    Salts: Cocaine hydrochlorideCategories: Analgesics and Anesthetics