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Displaying results 181 - 190 of 10000 in total
  1. Drug

    Sennosides

    go.drugbank.com/drugs/DB11365
    ApprovedInvestigational

    Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase … It is a weaker laxative than bisacodyl or castor oil[A177092].

    Salts: Sennosides A and BMixtures: Senna-S, Senexon-S
  2. Drug

    Nelipepimut-S

    go.drugbank.com/drugs/DB06226
    Investigational

    Categories: Receptor Protein-Tyrosine Kinases, Receptor, Epidermal Growth FactorSynonyms: Human receptor tyrosine-protein kinase erbB-2 (proto-oncogene Neu, tyrosine kinase-type cell surface receptor HER2, CD340)-(347-355)-peptide, Nelipepimut S
  3. Pathway

    Sphingolipid Signaling (Receptor)

    smpdb.ca/view/SMP0524344
    Signaling

    Through these receptor‑specific G protein couplings—spanning cAMP suppression, Ca²⁺ mobilization, PKC activation, Rho GTPase–driven cytoskeletal remodeling, and PI3K/Akt and MAPK pathways—S1P orchestrates

    Drugs: Nitric Oxide · Calcium · Magnesium cation
    Enzymes: Sphingosine 1-phosphate receptor 2, Sphingosine 1-phosphate receptor 4
  4. Drug

    TOL-101

    go.drugbank.com/drugs/DB16980
    Investigational

    Synonyms: Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor
  5. Drug

    Trastuzumab duocarmazine

    go.drugbank.com/drugs/DB16342
    Investigational

    Trastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens erbb2 (epidermal growth factor receptor 2, receptor tyrosineprotein kinase erbb-2, egfr2, her2, her-2, p185cerbb2, neu, cd340)), humanized monoclonal antibodyCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors
  6. Drug

    Water

    go.drugbank.com/drugs/DB09145
    ApprovedInvestigational

    As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. … Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms.

    Mixtures: IC-Green, IC-GreenProducts: Green Guard First Aid Eye Wash, N/A
  7. Drug

    Becotatug

    go.drugbank.com/drugs/DB19069
    Investigational

    JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor

    Synonyms: Immunoglobulin G1, anti-(human epidermal growth factor receptor) (human-Mus musculus monoclonal JMT101 γ1-chain), disulfide with human-Mus musculus monoclonal JMT101 κ-chain, dimer, Jmt101 (fully human monoclonal igg1 antibody targeting epidermal growth factor receptor (egfr))
  8. Drug

    EDI-200

    go.drugbank.com/drugs/DB18188
    Investigational

    EDI-200 is a fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1.

    Synonyms: HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN
  9. Drug

    Ibutilide

    go.drugbank.com/drugs/DB00308
    Approved

    It is indicated for the conversion of acute atrial flutter and recent onset atrial fibrillation to normal sinus rhythm (NSR). … Ibutilide is a Class III antiarrhythmic agent available in intravenous formulations.

    Synonyms: N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamideProducts: Fybrio 1 mg/10 ml I.V. Enjeksiyonluk Çözelti, 1 ADET
  10. Drug

    Recombinant human alkaline phosphatase

    go.drugbank.com/drugs/DB17672
    Investigational

    Synonyms: recAP