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Displaying results 181 - 190 of 10000 in total
  1. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily. … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia.

    Mixtures: Innovar InjCategories: Fentanyl and fentanyl analogues
  2. Drug

    PRGN-3006

    go.drugbank.com/drugs/DB17229
    Investigational

    PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface

    Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surface
  3. Drug

    DCLL-9718S

    go.drugbank.com/drugs/DB17392
    Investigational

    DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). … DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer
  4. Drug

    Zinc oxide

    go.drugbank.com/drugs/DB09321
    ApprovedInvestigational

    Zinc oxide is an inorganic compound used in a number of manufacturing processes. … It occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically.

    Mixtures: Your Skin But Better Cc Eye Tan, Cal-mag Plus K, Mn and Zn CapletsCategories: Compounds used in a research, industrial, or household setting, Basic Powders and Demulcents
  5. Drug

    Nicotinamide

    go.drugbank.com/drugs/DB02701
    ApprovedInvestigational

    An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. … Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

    Mixtures: Lebody Bu W Renewal Up, Niacinamide 250mg With 50mg CCategories: Alimentary Tract and Metabolism
  6. Drug

    Riboflavin

    go.drugbank.com/drugs/DB00140
    ApprovedInvestigationalNutraceuticalVet approved

    It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. … Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast.

    Mixtures: B-2 100mg With C 20mg, Stress Formula Multi-B Comp + 500mg Vit C CapCategories: Enzymes and Coenzymes, Alimentary Tract and Metabolism
  7. Drug

    Methoxy polyethylene glycol-epoetin beta

    go.drugbank.com/drugs/DB09107
    ApprovedInvestigational

    ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia. … Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin.

    Categories: Compounds used in a research, industrial, or household setting, Blood and Blood Forming OrgansProducts: MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 50MCG/0.3ML, MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 100MCG/0.3ML
  8. Drug

    Dabocemagene autoficel

    go.drugbank.com/drugs/DB17878
    Investigational

    Dabocemagene autoficel is an _ex vivo_, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. … Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.[L46797]

    Synonyms: AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING, SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER, 2004-TRANSDUCED HUMAN AUTOLOGOUS DYSTROPHIC EPIDERMOLYSIS BULLOSA DERMAL FIBROBLAST CELL FCX-007 INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND
  9. Drug

    Fluconazole

    go.drugbank.com/drugs/DB00196
    ApprovedInvestigational

    It was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. … Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues.

    Mixtures: FLUCONAZOL+SECNIDAZOL 75MG/1000 MG, FLUCONAZOL+SECNIDAZOL 75MG/1000 MGCategories: Imidazole and Triazole Derivatives, Triazole and tetrazole derivatives
  10. Drug

    STRO-001

    go.drugbank.com/drugs/DB17224
    Investigational

    Synonyms: antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable maytansinoid linker warheads