Zinc oxide



Zinc oxide is a mineral ingredient of various pharmacological preparations to treat diaper dermatitis and other skin conditions, to protect the epidermis, and to prevent sunburn.

Brand Names
A+d Diaper Rash, Baby Anti Monkey Butt Diaper Rash Powder, Balmex, Caladryl, Calazime Skin Protectant, Caldesene, Calmodrox, Calmol, Calmoseptine Ointment, Carlesta, Critic-aid Skin, Dermacinrx Therazole Pak, Desitin, Dr. Smith's Diaper Rash, Dyna1199 with Dimethicone, Dynashield, Dynashield Zo, Eucerin, Flanders, Gold Bond Baby Cornstarch Plus, Pregvit, Rash Relief Antibacterial, Rash Relief Antifungal, Rash Relief With Zinc Oxide, Soothe & Cool Skin Paste, Triple Paste, Tronolane Anesthetic, Vusion, Z-bum, Zincofax
Generic Name
Zinc oxide
DrugBank Accession Number

Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically. It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.

Small Molecule
Average: 81.408
Monoisotopic: 79.9240612
Chemical Formula
  • óxido de cinc
  • oxyde de zinc
  • Zinc (as oxide)
  • Zinc (as zinc oxide)
  • Zinc oxide
  • Zinc óxido
  • Zinc white
  • Zinci oxydum
  • Zincum oxydatum
  • Zinkoxid
External IDs
  • C.I. 77947
  • C.I. pigment white 4
  • CI 77947



For adjunctive treatment of diaper dermatitis. Also, it can be used to treat minor skin irritations (eg, cuts, burns, and scrapes, poison ivy). Zinc oxide can be used in ointments, creams, and lotions to protect against sunburn and other damage to the skin caused by ultraviolet light.

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatAcute woundsCombination Product in combination with: Witch hazel (DB11111)••• ••••••••
Used in combination to treatBurns first degreeCombination Product in combination with: Cod liver oil (DB11321)••• •••••••••••
Used in combination to treatBurns first degreeCombination Product in combination with: Witch hazel (DB11111)••• ••••••••
Used in combination to treatBurns second degreeCombination Product in combination with: Witch hazel (DB11111)••• ••••••••
Used in combination to treatDermatitis, eczematousCombination Product in combination with: Dimethicone (DB11074), Mineral oil (DB11057)••• ••••••••••••••
Associated Therapies
Contraindications & Blackbox Warnings
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Zinc oxide has astringent, soothing and protective properties and is used in topical preparations for eczema, slight excoriations, wounds and haemorrhoids. It also reflects ultraviolet radiation and can be used as a physical sunscreen.

Mechanism of action

It acts by providing a physical barrier to prevent skin irritation and help heal damaged skin.


No significant percutaneous absorption from topically applied zinc oxide.

Volume of distribution

Intended for local use only, no systemic absorption.

Protein binding

Intended for local use only, no systemic absorption.


Intended for local use only, no systemic absorption.

Route of elimination

Intended for local use only, no systemic absorption.


Intended for local use only, no systemic absorption.


Intended for local use only, no systemic absorption.

Adverse Effects
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Acute oral toxicity (LD50) in mice: 7950 mg/kg.2 The acute respiratory LD50 in mice is 2500 mg/m3.2

Not Available
Pharmacogenomic Effects/ADRs
Not Available


Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
CarbamazepineZinc oxide can cause a decrease in the absorption of Carbamazepine resulting in a reduced serum concentration and potentially a decrease in efficacy.
CeftibutenZinc oxide can cause a decrease in the absorption of Ceftibuten resulting in a reduced serum concentration and potentially a decrease in efficacy.
CephalexinZinc oxide can cause a decrease in the absorption of Cephalexin resulting in a reduced serum concentration and potentially a decrease in efficacy.
CinoxacinZinc oxide can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
CiprofloxacinZinc oxide can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Food Interactions
  • Avoid milk and dairy products. Separate the use of zinc from these products by at least 2 hours before administration. Separate for 2 hours after administration if these products also contain phosphorus.
  • Do not take with bran and high fiber foods. For optimal absorption, take zinc at least 2 hours before or after eating high-fiber foods.
  • Take on an empty stomach. Take at least 1 hour before and 2 hours after eating for optimal absorption. Zinc can be taken with food to reduce gastrointestinal upset.


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Active Moieties
Zinc cationionic13S1S8SF3723713-49-7PTFCDOFLOPIGGS-UHFFFAOYSA-N
Product Images
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
(Glow)Setting 100% Mineral Powder SPF 35Powder24.9 g/100gTopicalSupergoop, LLC2022-10-18Not applicableUS flag
(Re) Setting 100% mineral Powder Deep Broad Spectrum SPF 35Powder24.7 g/100gTopicalSupergoop, LLC2020-09-14Not applicableUS flag
(Re) Setting 100% mineral Powder Light Broad Spectrum SPF 35Powder24.7 g/100gTopicalSupergoop, LLC2020-09-08Not applicableUS flag
(RE) Setting 100% Mineral Powder Medium Broad Spectrum Sunscreen SPF 35Powder24.7 g/100gTopicalSupergoop, LLC2020-09-08Not applicableUS flag
(RE) Setting 100% Mineral Powder Translucent Broad Spectrum Sunscreen SPF 35Powder24.7 g/100gTopicalSupergoop, LLC2020-09-08Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
01 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
02 Cushion Spf45 SunscreenZinc oxide (8 g/100mL) + Octinoxate (5 g/100mL) + Octisalate (5 g/100mL) + Octocrylene (2.5 g/100mL) + Titanium dioxide (13.5 g/100mL)LiquidTopicalCOIZ CO LTD2019-06-30Not applicableUS flag
02 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
03 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
04 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
AbaviteZinc oxide (15 mg/1) + Ascorbic acid (60 mg/1) + Cholecalciferol (0.025 mg/1) + DL-alpha tocopheryl acetate (13.5 mg/1) + Ferrous sulfate (30 mg/1) + Folic acid (1 mg/1) + Magnesium oxide (25 mg/1) + Mecobalamin (0.5 mg/1) + Niacin (15 mg/1) + Calcium pantothenate (5 mg/1) + Potassium Iodide (0.25 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Vitamin A palmitate (0.33 mg/1)TabletOralABACOS HEALTH2021-03-31Not applicableUS flag
Active FEZinc oxide (20 mg/1) + Ascorbic acid (160 mg/1) + Beta carotene (2100 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (30 ug/1) + DL-alpha tocopheryl acetate (40 [iU]/1) + Folic acid (1250 ug/1) + Iron (75 mg/1) + Magnesium oxide (30 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (4 mg/1) + Thiamine hydrochloride (4 mg/1)TabletOralGm Pharmaceuticals2013-11-11Not applicableUS flag
Active OBZinc oxide (30 mg/1) + Ascorbic acid (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cupric sulfate pentahydrate (2 mg/1) + Cyanocobalamin (30 ug/1) + D-alpha-Tocopherol acetate (30 [iU]/1) + Doconexent (320 mg/1) + Folic acid (1 mg/1) + Iron (20 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (4 mg/1) + Thiamine mononitrate (2 mg/1)Capsule, liquid filledOralGm Pharmaceuticals2013-10-282017-03-31US flag
AHC Premium Intense Contour BalmZinc oxide (0.96 g/50mL) + Adenosine (0.02 g/50mL) + Aluminium tristearate (0.04 g/50mL) + Aluminum hydroxide (0.45 g/50mL) + Arbutin (1 g/50mL) + Methicone (20 CST) (1.3 g/50mL) + Octinoxate (1.5 g/50mL) + Talc (2.05 g/50mL) + Titanium dioxide (3.96 g/50mL)CreamTopicalCarver Korea Co.,Ltd.2014-01-152017-11-22US flag
All Day Err DayZinc oxide (5 g/100mL) + Nicotinamide (5 g/100mL)LiquidTopicalCOSMEDIQUE CO.,LTD.2020-04-01Not applicableUS flag


ATC Codes
C05AX04 — Zinc preparations
Drug Categories
Chemical TaxonomyProvided by Classyfire
This compound belongs to the class of inorganic compounds known as transition metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen is a transition metal.
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Transition metal organides
Sub Class
Transition metal oxides
Direct Parent
Transition metal oxides
Alternative Parents
Inorganic salts / Inorganic oxides
Inorganic oxide / Inorganic salt / Transition metal oxide
Molecular Framework
Not Available
External Descriptors
zinc molecular entity (CHEBI:36560)
Affected organisms
  • Humans and other mammals

Chemical Identifiers

CAS number
InChI Key


General References
  1. Derry JE, McLean WM, Freeman JB: A study of the percutaneous absorption from topically applied zinc oxide ointment. JPEN J Parenter Enteral Nutr. 1983 Mar-Apr;7(2):131-5. [Article]
  2. Fisher Scientific: Zinc oxide MSDS [Link]
  3. product info [Link]
PubChem Compound
PubChem Substance
FDA label
Download (112 KB)

Clinical Trials

Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package
PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
4CompletedTreatmentComplications; Cesarean Section / Postoperative Wound Infection / Satisfaction / Wound Breakdown / Wound Infections1somestatusstop reasonjust information to hide
4CompletedTreatmentDiabetes Complications1somestatusstop reasonjust information to hide
4CompletedTreatmentDiabetic Macular Edema (DME)1somestatusstop reasonjust information to hide
4CompletedTreatmentDiaper Rash2somestatusstop reasonjust information to hide
4CompletedTreatmentFungal Foot Infection1somestatusstop reasonjust information to hide


Not Available
Not Available
Dosage Forms
PowderTopical24.9 g/100g
LotionTopical20 mg/1mL
StickTopical87 mg/1g
Aerosol, sprayTopical120 mg/1mL
LotionTopical33.18 g/177mL
LotionTopical8.25 g/44mL
LotionTopical6.6375 g/6.6375g
CreamTopical0.2 g/80g
CreamCutaneous10 g
LotionTopical144 mg/1mL
LotionTopical11 g/100mL
LotionTopical7 g/100mL
LotionTopical8 g/100mL
CreamTopical4.97 g/100mL
CreamTopical142.8 mg/1mL
CreamTopical140 mg/1mL
OilTopical220 mg/1mL
CreamTopical12 mg/100mL
Capsule, liquid filledOral
CreamTopical1.6 mg/80mL
CreamTopical50 mg/1g
GelTopical5 mg/100mL
LotionTopical17 g/100g
CreamTopical100 mg/1mL
AerosolTopical18.3 g/100g
CreamTopical5.5 g/100g
StickTopical5.5 g/100g
LotionTopical0.1365 mg/1mL
CreamTopical13.5 g/100g
LotionTopical22.5 g/100g
CreamTopical17.5 g/100g
StickTopical4.14 g/18.4g
StickTopical11 g/100g
LotionTopical22 g/1
LotionTopical225 mg/1mL
PowderTopical5 g/100g
PowderTopical9.1 g/100g
LotionTopical20 g/100mL
LotionTopical0.16 g/1g
LipstickTopical8 g/100g
EmulsionTopical10 g/100mL
PatchCutaneous; Topical; Transdermal
OintmentRectal0.250 g
SprayTopical10 g/99g
StickTopical15 g/100g
LotionTopical15 g/100mL
CreamTopical21 g/100g
LotionTopical8.5 g/100g
CreamTopical130 mg/1g
LotionTopical120 mg/120mg
LotionTopical8 mg/1mL
StickTopical20.267 g/100g
SprayTopical14.5 g/100mL
LotionTopical206 mg/1mL
SprayTopical206 mg/1mL
SalveTopical245 mg/1g
SprayTopical145 mg/1mL
StickTopical15.326 g/100g
SprayTopical12.222 g/100mL
StickTopical24 g/100g
StickTopical17.9 g/100g
CreamTopical160 mg/1g
StickTopical192 mg/1g
CreamTopical200 mg/1mL
CreamTopical17.1 g/57g
CreamTopical10 g/10g
CreamTopical17 g/100g
OintmentTopical130 g/1g
CreamTopical16.51 g/127g
CreamTopical23.8 g/85g
CreamTopical2.75 g/11g
LotionTopical18 g/100g
CreamTopical0.75 g/60mL
OintmentTopical11.3 %
CreamTopical150 mg/1g
OintmentTopical16 g/100g
OintmentTopical16 mL/100mL
CreamTopical16 g/100g
OintmentTopical40 g
CreamTopical120 mg/1mL
LotionTopical12 g/100mL
CreamTopical22.5 g/100g
LotionTopical14 g/100mL
Cream; kitTopical10 g/100mL
CreamTopical18.75 g/100mL
StickTopical8 g/100g
StickTopical8.0 g/100g
CreamTopical20 g/100mL
LotionTopical20.0 g/100mL
StickTopical22.5 g/100g
OintmentTopical18.75 mL/100mL
CreamTopical22.5 g/100mL
LotionTopical10.55 g/100mL
CreamTopical10 g/100mL
CreamTopical10.0 g/100mL
CreamTopical0.113 g/1g
CreamTopical.113 g/1g
CreamTopical11.3 g/100g
StickTopical23.8 g/100g
StickTopical25 g/100mL
SprayTopical14 g/100mL
PowderTopical1440 mg/8g
PowderTopical20 g/100g
PowderTopical1600 mg/8g
OintmentTopical15 g/100g
CreamTopical100 mg/100mL
CreamTopical12 %
CreamTopical210 mg/1mL
CreamTopical5.0016 g/100mL
EmulsionTopical169 mg/1mL
EmulsionTopical168 mg/1mL
EmulsionTopical159 mg/1mL
EmulsionTopical144 mg/1mL
EmulsionTopical141 mg/1mL
LotionTopical110 mg/1mL
SprayTopical18 g/100mL
StickTopical15.4 g/100g
EmulsionTopical19 g/100mL
LipstickTopical8.05 g/100g
LotionTopical140 mg/1mL
LotionTopical149.6 mg/1mL
LotionTopical14.9 g/100mL
LotionTopical15.4 g/100mL
LotionTopical19 g/100mL
SprayTopical100 mg/1mL
CreamTopical17 mL/100mL
CreamTopical20 g
OintmentTopical0.10 g/1g
LotionTopical19.7 g/100mL
LotionTopical20.4 g/100mL
Spray, suspensionTopical
LotionTopical18 g/100mL
CreamTopical15.25 g/100g
CreamTopical188 mg/1mL
SuppositoryRectal200 mg
StickTopical20 mg/1g
SprayTopical24 mg/1g
CreamTopical34 g/85g
KitTopical19 g/100mL
OintmentTopical0.15 g/1g
OintmentTopical17.75 g/71g
CreamTopical9 g/71g
LotionTopical24 g/96g
LotionTopical17 g/66g
CreamTopical16 g/113g
CreamTopical40 g/113g
OintmentTopical16 g/113g
LipstickTopical15 g/100g
LotionTopical0.6375 g/4.25g
LotionTopical209 g/950g
CreamTopical14.4 g/100mL
StickTopical20 g/100g
StickTopical200 mg/1mL
LiquidTopical10 g/100mL
LotionTopical16.9 g/100g
SprayTopical4 g/100g
PasteTopical45.2 g/113g
CreamTopical14.69 g/113g
LotionTopical8 g
CreamTopical12 g/100g
CreamTopical16 g/70mL
CreamTopical120 mg/1g
CreamTopical9.2 g/40mL
LotionTopical12 g/100g
LiquidTopical18 g/100mL
LotionTopical9 g/100g
LotionTopical5 g/100g
LotionTopical13 mg/100mL
LotionTopical194 mg/1mL
CreamTopical194 mg/1mL
LotionTopical195 mg/1mL
Aerosol, sprayTopical15.2 g/100mL
Kit; stickTopical
StickTopical101 mg/1g
CreamTopical175 mg/1mL
LotionTopical145.7 mg/1mL
LotionTopical134.5 mg/1mL
CreamTopical12 g
CreamTopical1200000 g
CreamTopical20 mg/100mL
CreamTopical220 mg/1mL
LotionTopical120 mg/1mL
PasteTopical8.46 g/47g
OintmentTopical2.5 mg/1g
LotionTopical22.75 g/100mL
CreamTopical185 mg/1g
LotionTopical18.2 g/100mL
LotionTopical14.2 g/100mL
LotionTopical150 mg/1mL
LotionTopical158 mg/1mL
LotionTopical250.19 mg/1mL
StickTopical200 mg/1g
Aerosol, sprayTopical240.8 mg/1g
LotionTopical24.08 g/100g
LotionTopical240.8 mg/1mL
LotionTopical25.2 g/100mL
OintmentTopical0.4 g/1g
Aerosol, foamTopical
LotionTopical200 mg/1g
CreamTopical18.8 mg/100mg
CreamTopical19.72 mg/100mg
CreamTopical24.05 mg/100mg
OintmentTopical13.0 kg/100kg
OintmentTopical13.0 kg/1g
OintmentTopical5 g
OintmentTopical2 g
CreamTopical2 g
CreamTopical4 g
OintmentTopical49 mg/1g
CreamTopical10 g
CreamTopical15 g
CreamTopical25 g
CreamTopical20 %
PasteTopical200 mg/1g
PasteTopical20 %
OintmentTopical18 mg/1g
StickTopical94 mg/1g
CreamTopical14.7 g/113g
CreamTopical0.013 g/1g
LiquidTopical16.5 g/100mL
LotionTopical66 mg/1mL
LotionTopical10 g/100g
LotionTopical17.5 g/100g
CreamTopical12.5 g/100g
LotionTopical16.5 g/100mL
CreamTopical.135 mg/1g
LotionTopical160 mg/1mL
CreamTopical0.9 g/100mL
CreamTopical5.0 g/100g
CreamTopical18.67 g
LotionTopical95 mg/1mL
CreamTopical95 mg/1mL
CreamTopical152.5 mg/1g
CreamTopical12 g/100mL
OintmentTopical10 mg
PasteTopical400 mg/1g
OintmentTopical132.1 mg/1g
LotionTopical14.0 g/100mL
LotionTopical20.8 g/100mL
OintmentTopical40 g/100g
OintmentTopical21.76 g/100g
LotionTopical14 g/100g
CreamTopical0.1 g/1g
CreamTopical0.113 kg/1g
CreamTopical0.13 g/1g
CreamTopical0.40 g/1g
OintmentTopical.1 g/1g
OintmentTopical532 mg/1g
PasteTopical532 mg/1g
OintmentTopical0.2 g/1g
CreamTopical11 mg/50mg
CreamTopical15 g/100mL
CreamTopical19 g/100mL
LotionTopical12 g/88mL
OintmentTopical14 g/100g
CreamTopical4.9 g/100g
OintmentTopical12 %
CreamTopical96 mg/1g
CreamTopical182.2 mg/1mL
OintmentTopical30 g/100g
CreamTopical140 mg/1g
LotionTopical16.3 g/100g
SprayTopical17.5 g/100g
StickTopical17.6 g/100g
LotionTopical13 g/100g
OintmentTopical100 mg/1g
SprayTopical10 g/100g
LiquidTopical17 g/100mL
LiquidTopical16 g/100mL
GelTopical100 mg/1mL
OintmentTopical65 mg/1g
OintmentTopical10 g/100g
CreamTopical0.01248 g/1g
CreamTopical4.9004028 g/100mL
LotionTopical20 mg/100mL
LotionTopical170 mg/1mL
OintmentTopical250 mg/1g
OintmentTopical140 mg/1mL
OintmentTopical19 g/100g
CreamTopical215 mg/1g
CreamTopical24 g/100mL
OintmentTopical21 g/100g
PowderTopical15.004 g/100g
LotionTopical22 g/100g
LotionTopical105 mg/1mL
LotionTopical25 g/100mL
LiquidTopical25 g/100mL
CreamTopical9.8 g/100mL
CreamTopical13.8 g/100mL
CreamTopical75 g/1000g
LotionTopical20.2 g/100g
SprayTopical14.0 g/1000g
KitTopical200 mg/1mL
LiquidTopical150 mg/1mL
CreamTopical225 mg/100mL
StickTopical0.4 g/4g
CreamTopical59.02 g/454g
CreamTopical181.6 g/454g
CreamTopical216 mg/1mL
CreamTopical20 mL/100mL
EmulsionTopical11 g/100mL
LotionTopical107 mg/1mL
LotionTopical22.7 g/100g
LotionTopical22.00 g/100mL
LotionTopical24 g/100g
LotionTopical188 mg/1g
CreamTopical115 mg/1g
LotionTopical100 mg/1mL
CreamTopical163.2 mg/1mL
LotionTopical136 mg/1mL
CreamTopical177 mg/1mL
LotionTopical157 mg/1mL
LiquidCutaneous12 g/100mL
LotionTopical13.6 g/100mL
CreamTopical168 mg/1mL
CreamTopical101 mg/1mL
LotionTopical19 g/100g
OintmentRectal5.000 g
CreamTopical15.5 g/100mL
LotionTopical0.21 g/1g
LotionTopical17.8 g/100mL
LiquidTopical22 g/100mL
LiquidTopical13.8 g/100mL
PatchTopical8.3 g/100g
CreamTopical25 mL/100mL
CreamTopical19.2 g/100mL
LotionTopical6.05 g/30mL
SprayTopical150 mg/1g
CreamTopical0.125 mL/1mL
LiquidTopical0.65 mg/130mL
PasteTopical200 mg/1mL
CreamTopical189 mg/1g
Capsule, delayed releaseOral
LotionTopical0.1875 kg/1kg
CreamTopical205 mg/1g
SprayTopical20.8 g/100mL
CreamTopical125 mg/1mL
CreamTopical190 mg/1g
PowderTopical0.02 g/1g
LotionTopical13.3 g/100mL
CreamTopical0.10 g/1g
CreamTopical13 mg/1g
LotionTopical9.7 g/100mL
PasteOral400 mg/1g
CreamTopical1.92 g/100mL
LotionTopical182.3 mg/1mL
CreamTopical18.0 g/100mL
LotionTopical15.2 g/100mL
CreamTopical3 mg/100mL
GelTopical0.025 mg/100mL
LiquidTopical160 mg/1mL
Kit; lotion; paste, dentifriceDental; Topical
CreamTopical18 g/100mL
LotionTopical25 g/100g
SolutionTopical160 mg/1mL
StickTopical9.2 g/100g
OintmentRectal50 mg/1g
PowderTopical12.5 g/100g
CreamTopical19.24 g/100mL
CreamTopical17.5 g/100mL
OintmentTopical150 mg / g
CreamTopical175.3 mg/1mL
LotionTopical175.3 mg/1mL
CreamCutaneous21.6 g/100mL
PowderTopical20 g
OintmentTopical15 g
CreamTopical32 % w/w
LotionTopical9.3 g/100mL
Spray, suspensionTopical12 g/100mL
CreamTopical11.25 g/60g
CreamTopical10.0 g/100g
CreamTopical2.3175 g/15g
CreamTopical7.725 mg/50mg
CreamTopical0.03 g/1mL
PowderTopical0.0192 g/1g
PowderTopical0.0291 g/1g
LotionTopical13.5 g/100g
PasteTopical25 %
CreamTopical110 g/1000g
CreamTopical171 g/1000g
Tablet, coatedOral
CreamTopical14.5 mg/1mL
PowderTopical24.5 g/100g
LiquidTopical15 g/100mL
LotionTopical20.9 mg/1mL
CreamTopical15.52 g/50mL
LiquidTopical1.6 g/100g
LiquidTopical24.5 mg/100mL
LiquidTopical245 mg/1mL
CreamTopical0.07 g/1g
CreamTopical0.0192 g/1g
LiquidTopical0.02 g/1g
PowderTopical10 g
CreamTopical13.0 %
PowderTopical10 %
Cream; kitTopical130 mg/1g
KitTopical130 mg/1g
PowderTopical100 mg/1g
Kit; pasteTopical400 mg/1g
Cream, augmentedTopical
LotionTopical17 g/100mL
SolutionTopical18 g/100mL
PasteTopical30 g/100g
OintmentTopical10 mL/100mL
CreamTopical20.2 g/100g
Capsule, coatedOral
StickTopical210 mg/1g
LotionTopical98.56 g/448g
LiquidTopical20.8 g/100mL
OintmentTopical250 g/1000g
LotionTopical20.3 g/100g
StickTopical18 g/100g
CreamTopical150 mg/88mL
LotionTopical15 g/100g
LotionTopical15 mg/100mL
CreamTopical16.96 mg/80mL
LotionTopical150 mg/1g
StickTopical25 g/100g
LotionTopical0.0157 g/1mL
LotionTopical0.48 g/30mL
LiquidTopical.016 g/1mL
LiquidTopical0.016 g/1mL
Lotion / shampooTopical
CreamTopical4 g/10g
CreamTopical80 mg/1g
CreamTopical9.45 mg/1mL
CreamTopical6.8 g/100mL
CreamTopical170 mg/1g
CreamTopical227.5 mg/1mL
OintmentTopical113.6 g/284g
CreamTopical3.8 g/100g
OintmentTopical3.8 g/100g
LotionTopical30 g/150g
StickTopical10.5 g/100g
StickTopical15.45 g/100g
StickTopical8.55 g/100g
LipstickTopical105 mg/1mL
LiquidTopical66 mg/1mL
LipstickTopical17.5 g/100g
LotionTopical7.9 mg/100mL
Cream; kit; liquidOral; Topical
Cream; kitTopical182.3 mg/1mL
CreamTopical182.3 mg/1mL
GelTopical245 mg/1g
SuspensionTopical8.14 g
LotionTopical204 mg/1mL
CreamTopical155 mg/1mL
CreamTopical14 g/100mL
OintmentTopical180 mg/1g
OintmentTopical18 g/100g
OilTopical132.2 mg/1mL
Cream; kitTopical12 g/100mL
OintmentTopical1 g/100g
CreamTopical0.0098 g/1g
CreamTopical400 mg/1g
OintmentRectal; Topical
SuppositoryRectal1.7 g/1
CreamTopical50 mg/1mL
DressingTopical19.8 g/165g
DressingTopical24.6 g/205g
OintmentTopical96 mg/1g
OintmentTopical9.6 g/100g
CreamTopical1.8 g/100g
PasteTopical40 g/100g
LotionTopical6 g/100mL
PlasterTopical28.3 %
CreamTopical15.44 g/100mL
LiquidTopical270 mg/1mL
StickTopical0.34 g/4.25g
LotionTopical147 mg/1mL
CreamTopical135 mg/1mL
EmulsionTopical12.81 g/12.81g
EmulsionTopical23.814 g/113.4g
LotionTopical0.25 mg/1mg
LotionTopical22.8 g/100mL
CreamTopical50.0 mg/1mL
LipstickTopical80 mg/1g
PowderTopical127 mg/1g
Aerosol, sprayTopical20.5 g/100g
SprayTopical140 mg/1g
StickTopical13.63 g/100g
StickTopical17 g/100g
CreamTopical22400 mg/118.3mL
CreamTopical24 mg/1g
CreamCutaneous3.5 mL/50mL
CreamTopical5 g/100g
LotionTopical175 mg/1mL
CreamTopical22.4 mg/100mg
LotionTopical17.68 mg/100mg
CreamTopical12.01 g/60mL
CreamTopical105 mg/1mL
LotionTopical19.5 g/100g
Tablet, chewableOral
EmulsionTopical17 g/100g
CreamTopical9.9 g/100g
CreamTopical149 mg/1mL
SprayTopical120 mg/1mL
LotionTopical240 mg/1mL
StickTopical197 mg/1g
LotionTopical8.3 g/83g
LotionTopical5.5 g/55g
CreamTopical7 g/100mL
LotionTopical21 g/100mL
LotionTopical13.5 g/100mL
LiquidTopical16.1 g/100mL
LiquidTopical20.5 g/100mL
LiquidTopical20 g/100mL
StickTopical21.8 g/100g
SprayTopical3 g/100mL
CreamTopical195 mg/1mL
LotionTopical5.625 g/30mL
CreamTopical189 mg/1mL
CreamTopical7.85 g/50mL
LotionTopical24 g/68mL
CreamTopical24.96 g/100g
LotionTopical22 g/100mL
OintmentTopical8.8 g/88mL
LotionTopical15.002 g/100mL
CreamTopical19.92375 g/100mL
Capsule, gelatin coated; kit; tabletOral
LotionTopical182.4 mg/1mL
LotionTopical216 mg/1mL
LotionTopical182 mg/1mL
StickTopical216 mg/1g
LotionTopical8.5 g/100mL
GelTopical20 g/100g
LiquidTopical1.38 g/10g
EmulsionTopical0.7434 g/9g
LiquidTopical2.478 g/30g
LipstickTopical0.315 g/4.2g
LipstickTopical0.1764 g/4.2g
LotionTopical17.5 g/100mL
CreamTopical.12 mL/1mL
LotionTopical185 mg/1g
Cream; kit; lotionTopical
LipstickTopical15 g/100mL
StickTopical10 g/100g
StickTopical5 g/100g
KitTopical175 mg/1mL
LotionTopical12.4 g/100mL
SprayTopical15 g/100mL
LotionTopical17.6 g/100mL
LotionTopical19.6 g/100mL
Kit; liquid; lotionTopical
Cream; kit; liquid; lotionTopical
Capsule, liquid filled; kit; tablet, film coatedOral
LotionTopical16.32 g/100mL
StickTopical5.7 g/100g
CreamTopical17 g/100mL
LipstickTopical10 g/100g
LotionTopical15.7 g/100mL
Kit; sprayTopical
PasteCutaneous25.000 g
LotionTopical8.2 g
SuspensionTopical8 g
CreamTopical114 mg/1mL
OintmentTopical0.08 g/56g
LotionTopical170 mg/1g
PasteTopical25 g
CreamTopical250 mg/1g
PasteTopical20 g
PasteTopical180 mg / g
PowderTopical192 mg/1mL
PasteTopical25 g/100g
LotionTopical13.0 %
CreamTopical225 mg/1mL
CreamTopical2.4 g/0.259mL
LotionTopical0.12 g/1mL
PowderTopical25 g/100g
OintmentTopical0.038 g/1g
CreamTopical60 g/1000g
LotionTopical0.13 mg/2.5mL
OintmentTopical300 mg/1g
LotionTopical20.2 g/100mL
LipstickTopical10.5 g/100g
CreamTopical4.7 g/100mL
PasteTopical25 % w/w
PowderTopical24.7 g/100g
LotionTopical10 mg/100mL
PowderTopical24.5 mg/100mg
Capsule, liquid filled; kit; tablet, coatedOral
CreamTopical20 g/100g
OintmentTopical20 g/100g
Tablet, film coatedOral
Capsule, liquid filled; kit; tabletOral
GelTopical110 mg/1mL
CreamTopical18 mg/1g
PowderTopical250 mg/1g
CreamTopical5 g/1mL
CreamTopical210 mg/1g
CreamTopical15.6 g/100g
CreamTopical7.5 g/100g
LotionTopical1 g/5g
LiquidTopical0.0098 g/1mL
PowderTopical15 g/142g
CreamTopical180 mg/1mL
CreamTopical180 mg/1g
LiquidTopical76 mg/1mL
SalveTopical20 g/100g
CreamTopical15 g/100g
LotionTopical7.5 mL/100mL
CreamTopical1.6 g/20mL
CreamTopical13 g/100g
CreamTopical15.5 g/100g
CreamTopical4.9 g/100mL
OintmentTopical.20 g/1g
CreamTopical18.5 g/100g
LotionTopical250 mg/1g
StickTopical250 mg/1g
StickTopical227.5 mg/1g
CreamTopical230 mg/1mL
LotionTopical230 mg/1g
CreamTopical227.5 mg/1g
CreamTopical49.5 mg/1g
KitTopical4.95 mg/3g
LotionTopical49.5 mg/1mL
Kit; lotionTopical49.5 mg/1mL
CreamTopical4.45 g/100g
Kit; lotionTopical
CreamTopical49 mg/1g
CreamTopical0.8 g/100mL
CreamTopical2 g/100mL
CreamTopical25 g/100mL
LotionTopical21 g/112g
PasteTopical20 g/100g
Cream; kitTopical220 mg/1mL
CreamCutaneous21.8 g/100mL
SprayCutaneous21.8 g/100mL
DressingTopical25 g/1
CreamTopical13 g/100mL
ClothTopical150 mg/1g
CreamTopical0.0686 mg/1g
PasteTopical220 mg/1g
OintmentTopical400 mg/1g
CreamTopical20.5 g/100g
EmulsionTopical200 mg/1mL
CreamTopical.9 mL/30mL
PasteCutaneous25.00 g
StickTopical35 mg/1g
CreamTopical8 g/90mL
CreamTopical0.6 mg/15mL
CreamTopical0.26 g/1.54g
LotionTopical195 mg/1g
CreamTopical150 mg/1mL
LotionTopical228 mg/1mL
LotionTopical196 mg/1mL
StickTopical240 mg/1g
StickTopical240.5 mg/1g
StickTopical0.08 g/1g
StickTopical0.2405 g/1g
CreamCutaneous25.000 g
LotionTopical0.75 g/5mL
PowderTopical18 g/100g
Capsule, gelatin coatedOral
SolutionTopical120 mg/1mL
SolutionTopical170 mg/1mL
SolutionTopical180 mg/1mL
CreamTopical306.1 mg/1g
CreamTopical100 mg/1g
Capsule; kit; tablet, coatedOral
CreamTopical224 mg/1g
CreamTopical2 kg / 100 kg
Aerosol, foamTopical140 mg/1mL
PowderTopical12 mg/0.1g
PowderTopical12 mg/100mg
CreamTopical11.6 mg/100mL
LotionTopical10.5 g/100mL
CreamTopical0.0135 g/1g
LotionTopical14.5 g/100mL
CreamTopical21 g/100mL
CreamTopical40 g/100g
PowderTopical5 %
CreamTopical0.1995 g/1g
Cream; kitTopical
LotionTopical19 g/142g
LotionTopical25 g/142g
OintmentTopical25 mg/100mg
Cream; kit; liquidTopical
PasteTopical12.5 g/100g
GelTopical10 g/100g
CreamTopical0.1 g/1mL
LipstickTopical0.462 g/4.62g
LotionTopical23.7 g/118.294g
OintmentTopical0.085 g/1g
StickTopical1.14 g/6.8g
OintmentTopical55 mg/1g
LipstickTopical65 mg/1g
CreamTopical.0702 mg/1g
LotionTopical22.75 g/100g
CreamTopical200 mg/1g
CreamTopical11 g/100mL
CreamTopical223 mg/1g
StickTopical100 mg/1g
CreamTopical10.8 g/96g
CreamTopical2.94 g/28g
CreamTopical.15 g/1g
CreamTopical9.3154 g/100g
LotionTopical20 g/100g
StickTopical3.06 g/17g
LotionTopical227 mg/1mL
CreamTopical186 mg/1mL
LotionTopical2495 g/501mL
StickTopical225 mg/1g
StickTopical17.363 g/100g
StickTopical20.2115 g/100g
Kit; lipstickTopical
CreamTopical21.4 g/100mL
LotionTopical220 mg/1mL
LotionTopical215 mg/1mL
LipstickTopical22.75 g/100g
StickTopical220 mg/1g
Aerosol, sprayTopical
SprayTopical10 g/100mL
KitTopical12 g/100mL
LiquidTopical8.82 g/90mL
LotionTopical16 g/100mL
CreamTopical94 mg/1mL
CreamTopical24.5 g/100mL
SprayTopical140 mg/1mL
StickTopical80 mg/1g
StickTopical190 mg/1g
StickTopical18 g/100mL
CreamTopical220 mg/1g
LiquidTopical14.5 g/100mL
CreamTopical16 g/100mg
CreamTopical22 g/100mL
SprayTopical12 g/100mL
StickTopical17 g/100mL
GelTopical186 mg/1mL
CreamTopical190 mg/1mL
CreamTopical170 mg/1mL
CreamTopical43.4 g/177mL
CreamTopical28.9 g/118mL
Kit; lotion; stickTopical
CreamTopical25 g/100g
LiquidTopical50 mg/1mL
LotionTopical1 g/1g
LotionTopical134.4 mg/1mL
PowderTopical225 mg/1g
StickTopical135 mg/1g
LotionTopical4.5 g/30mL
LotionTopical12.5 g/100mL
CreamTopical22.75 g/100mL
LotionTopical126 mg/1mL
StickTopical21 g/100g
CreamTopical19 g/100g
CreamTopical24 mg/100mg
EmulsionTopical21 g/100g
OilTopical20 g/100g
OintmentTopical20 g/84g
OintmentTopical22 g/100g
OintmentTopical25 g/100g
OintmentTopical50 g/100g
SprayTopical14 g/100g
CreamTopical14.57 g/100mL
LotionTopical22 mg/100mg
EmulsionTopical9.919 g/61g
CreamTopical6 mg/40mL
CreamTopical17.6 mg/80mg
PowderCutaneous25 g/100g
CreamTopical12 mg/80mL
LotionTopical12.9 mL/52mL
LotionTopical1.24 mL/5mL
LotionTopical32.3 mL/130mL
LipstickTopical18 g/100g
CreamTopical882.7 mg/9.1g
StickTopical24.5 g/100g
LotionTopical30 mg/1mL
PowderTopical12 g/100g
PowderTopical16 g/100g
OintmentTopical9 g/75g
PasteTopical100 g/14mL
LotionTopical0.15 g/1g
LotionTopical10 g/100mL
Cream; kitTopical14 g/100g
EmulsionTopical120 mg/1mL
EmulsionTopical240 mg/1mL
LotionTopical25 g/120g
LotionTopical234 mg/1g
StickTopical200 ug/1g
LotionTopical200 mg/1mL
StickTopical105 ug/1g
StickTopical75 mg/1g
CreamTopical176.7 mg/1g
StickTopical19 g/100g
CreamTopical10 g/100g
CreamTopical90 mg/1g
CreamTopical0.12 g/1g
CreamTopical0.2 g/1g
LotionTopical205 mg/1g
SprayTopical25 g/100g
CreamTopical1.15 g/40mL
CreamTopical12.4 g/100g
StickTopical22 g/100g
SprayTopical15 g/100g
LotionTopical20.5 g/100g
LotionTopical130 mg/1mL
CreamTopical10 %
OintmentTopical12.8 g/100g
PasteTopical12.8 g/100g
Capsule; kit; tablet, film coatedOral
CreamTopical18.6 g/100g
CreamTopical20 mg/100mg
LotionTopical20 mL/100mL
SprayTopical24 mL/120mL
CreamTopical10 mL/50mL
PowderTopical0.25 g/1g
CreamTopical11.4 g/100mL
CreamTopical0.135 mg/1g
OintmentTopical25 g
OintmentTopical3.5 g
OintmentTopical20 g
DressingTopical3 mg/1cm2
PasteTopical5 mg/1cm2
CreamTopical.07 g/1g
OintmentTopical13.0 g/100g
OintmentTopical40.0 g/100g
CreamTopical149.5 mg/1mL
CreamTopical182 mg/1mL
LotionTopical15.5 g/100mL
CreamTopical19.5 g/100g
LotionTopical6.87 g/34.35g
Capsule; kit; tabletOral
CreamTopical6.00 g/50mL
PasteTopical125 mg/1g
PowderTopical0.69 g/3g
PowderTopical2 g/100g
OintmentTopical0.40 g/1g
CreamTopical24 g/100g
LiquidTopical24 g/100mL
PowderTopical24 g/100g
LotionTopical146 mg/1mL
CreamTopical14 g/100g
ClothTopical20 g/100g
LotionTopical190 mg/1mL
LotionTopical129.6 mg/1mL
LotionTopical122.4 mg/1mL
LotionTopical154 mg/1mL
LotionTopical73.6 mg/1mL
LotionTopical132 mg/1mL
LotionTopical135.6 mg/1mL
LotionTopical127 mg/1mL
StickTopical150 mg/1g
StickTopical125 mg/1g
LotionTopical174 mg/1mL
LotionTopical12 mg/1mL
LotionTopical128 mg/1mL
OintmentTopical0.5 g/100g
StickTopical7.6 g/100g
StickTopical6.5 g/100g
CreamTopical157 mg/1mL
LotionTopical210 mg/1mL
CreamTopical1.96 g/100g
CreamTopical22 g/100g
LotionTopical8 g/100g
LotionTopical11 g/90g
LotionTopical22 g/90g
CreamTopical15 %
LotionTopical25 g/240g
OintmentTopical15 %
CreamTopical0.2 kg/1kg
CreamTopical480 g/1000mL
LotionTopical12.5 g/100g
OintmentTopical.2 g/1g
OintmentTopical1.8 g/100g
OintmentTopical160 mg/1g
OintmentTopical20 kg/100kg
OintmentTopical200 mg/1g
Spray, suspensionTopical250 mg/1mL
StickTopical22 g/100mL
CreamTopical40 g/100mL
CreamTopical15 g / 100 g
OintmentTopical20 g / 100 g
OintmentTopical20 %
LotionTopical13 g/100mL
LiquidNot applicable50 kg/100kg
CreamTopical186 mg/1g
OintmentTopical40 %
CreamTopical25 kg/100kg
DressingTopical20 %
OintmentRectal50 mg
ClothTopical0.1 g/100mL
LotionTopical0.225 g/50mL
PowderTopical0.675 mg/2.7g
PowderTopical0.675 mg/1g
LotionTopical24 g/100mL
Cream7.5 %w/w
Not Available
Patent NumberPediatric ExtensionApprovedExpires (estimated)Region
US8147852No2012-04-032028-03-30US flag


Experimental Properties
Not Available
Predicted Properties
pKa (Strongest Basic)-5.7Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area17.07 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity1.44 m3·mol-1Chemaxon
Polarizability3 Å3Chemaxon
Number of Rings0Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available


Mass Spec (NIST)
Not Available
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at November 17, 2015 17:38 / Updated at July 14, 2024 17:59