Zinc oxide

Identification

Name
Zinc oxide
Accession Number
DB09321
Description

Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically. It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.

Type
Small Molecule
Groups
Approved
Structure
Thumb
Weight
Average: 81.408
Monoisotopic: 79.9240612
Chemical Formula
OZn
Synonyms
  • óxido de cinc
  • oxyde de zinc
  • Zinc (as oxide)
  • Zinc (as zinc oxide)
  • Zinc óxido
  • Zinc white
  • Zinci oxydum
  • Zincum oxydatum
  • Zinkoxid
External IDs
  • C.I. 77947
  • C.I. pigment white 4
  • CI 77947

Pharmacology

Indication

For adjunctive treatment of diaper dermatitis. Also, it can be used to treat minor skin irritations (eg, cuts, burns, and scrapes, poison ivy). Zinc oxide can be used in ointments, creams, and lotions to protect against sunburn and other damage to the skin caused by ultraviolet light.

Associated Conditions
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
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Pharmacodynamics

Zinc oxide has astringent, soothing and protective properties and is used in topical preparations for eczema, slight excoriations, wounds and haemorrhoids. It also reflects ultraviolet radiation and can be used as a physical sunscreen.

Mechanism of action

It acts by providing a physical barrier to prevent skin irritation and help heal damaged skin.

Absorption

No significant percutaneous absorption from topically applied zinc oxide.

Volume of distribution

Intended for local use only, no systemic absorption.

Protein binding

Intended for local use only, no systemic absorption.

Metabolism

Intended for local use only, no systemic absorption.

Route of elimination

Intended for local use only, no systemic absorption.

Half-life

Intended for local use only, no systemic absorption.

Clearance

Intended for local use only, no systemic absorption.

Adverse Effects
Learn about our commercial Adverse Effects data.
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Toxicity

Acute oral toxicity (LD50): 7950 mg/kg [Mouse].

Affected organisms
  • Humans and other mammals
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
CarbamazepineZinc oxide can cause a decrease in the absorption of Carbamazepine resulting in a reduced serum concentration and potentially a decrease in efficacy.
CeftibutenZinc oxide can cause a decrease in the absorption of Ceftibuten resulting in a reduced serum concentration and potentially a decrease in efficacy.
CephalexinZinc oxide can cause a decrease in the absorption of Cephalexin resulting in a reduced serum concentration and potentially a decrease in efficacy.
CinoxacinZinc oxide can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
CiprofloxacinZinc oxide can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
DeferasiroxZinc oxide can cause a decrease in the absorption of Deferasirox resulting in a reduced serum concentration and potentially a decrease in efficacy.
DeferiproneZinc oxide can cause a decrease in the absorption of Deferiprone resulting in a reduced serum concentration and potentially a decrease in efficacy.
DelafloxacinZinc oxide can cause a decrease in the absorption of Delafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
DemeclocyclineZinc oxide can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
DolutegravirZinc oxide can cause a decrease in the absorption of Dolutegravir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
  • Avoid milk and dairy products. Separate the use of zinc from these products by at least 2 hours before administration. Separate for 2 hours after administration if these products also contain phosphorus.
  • Do not take with bran and high fiber foods. For optimal absorption, take zinc at least 2 hours before or after eating high-fiber foods.
  • Take on an empty stomach. Take at least 1 hour before and 2 hours after eating for optimal absorption. Zinc can be taken with food to reduce gastrointestinal upset.

Products

Active Moieties
NameKindUNIICASInChI Key
ZincunknownJ41CSQ7QDS7440-66-6HCHKCACWOHOZIP-UHFFFAOYSA-N
Zinc cationionic13S1S8SF3723713-49-7PTFCDOFLOPIGGS-UHFFFAOYSA-N
Product Images
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
(Re) Setting 100% mineral Powder Deep Broad Spectrum SPF 35Powder24.7 g/100gTopicalTaylor James, Ltd.2020-09-14Not applicableUS flag
(Re) Setting 100% mineral Powder Light Broad Spectrum SPF 35Powder24.7 g/100gTopicalTaylor James, Ltd.2020-09-08Not applicableUS flag
(RE) Setting 100% Mineral Powder Medium Broad Spectrum Sunscreen SPF 35Powder24.7 g/100gTopicalTaylor James, Ltd.2020-09-08Not applicableUS flag
(RE) Setting 100% Mineral Powder Translucent Broad Spectrum Sunscreen SPF 35Powder24.7 g/100gTopicalTaylor James, Ltd.2020-09-08Not applicableUS flag
100% Pure Argan Oil Moisturizer SPF 30Lotion20 mg/1mLTopicalPurity Cosmetics2014-09-032017-05-01US flag
100% Pure Sweet Mint Lip Balm SPF 15Stick87 mg/1gTopicalPurity Cosmetics2017-05-01Not applicableUS flag
100% Pure Yerba Mate MIst SPF 30Aerosol, spray120 mg/1mLTopicalPurity Cosmetics2017-05-01Not applicableUS flag
1000 Roses CC Color plus Correct Sheer Nude SPF 30Lotion200 mg/1mLTopicalAndalou Naturals2014-03-01Not applicableUS flag
1000 Roses CC Color Plus Correct Sheer Tan SPF 30Lotion200 mg/1mLTopicalAndalou Naturals2014-03-01Not applicableUS flag
365 Everyday ValueLotion33.18 g/177mLTopicalWhole Foods Market, Inc.2019-02-01Not applicableUS flag
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
01 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
02 Cushion Spf45 SunscreenZinc oxide (8 g/100mL) + Octinoxate (5 g/100mL) + Octisalate (5 g/100mL) + Octocrylene (2.5 g/100mL) + Titanium dioxide (13.5 g/100mL)LiquidTopicalCOIZ CO LTD2019-06-30Not applicableUS flag
02 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
03 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
04 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
05 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
06 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
07 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
08 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUS flag
100% Mineral Body Mist With Green Tea Extract Broad Spectrum SPF 50Zinc oxide (12 g/100mL) + Titanium dioxide (10 g/100mL)LiquidTopicalTaylor James, Ltd.2020-05-01Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Active FEZinc oxide (20 mg/1) + Ascorbic acid (160 mg/1) + Beta carotene (2100 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (30 ug/1) + DL-alpha tocopheryl acetate (40 [iU]/1) + Folic acid (1250 ug/1) + Iron (75 mg/1) + Magnesium oxide (30 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (4 mg/1) + Thiamine hydrochloride (4 mg/1)TabletOralGm Pharmaceuticals2013-11-11Not applicableUS flag
Active OBZinc oxide (30 mg/1) + Ascorbic acid (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cupric sulfate pentahydrate (2 mg/1) + Cyanocobalamin (30 ug/1) + D-alpha-Tocopherol acetate (30 [iU]/1) + Doconexent (320 mg/1) + Folic acid (1 mg/1) + Iron (20 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (4 mg/1) + Thiamine mononitrate (2 mg/1)Capsule, liquid filledOralGm Pharmaceuticals2013-10-282017-03-31US flag
AHC Premium Intense Contour BalmZinc oxide (0.96 g/50mL) + Adenosine (0.02 g/50mL) + Aluminium tristearate (0.04 g/50mL) + Aluminum hydroxide (0.45 g/50mL) + Arbutin (1 g/50mL) + Methicone (20 CST) (1.3 g/50mL) + Octinoxate (1.5 g/50mL) + Talc (2.05 g/50mL) + Titanium dioxide (3.96 g/50mL)CreamTopicalCarver Korea Co.,Ltd.2014-01-152017-11-22US flag
Baby ButzZinc oxide (17.1 g/57g) + Lanolin (8.8 g/57g) + Starch, corn (14.3 g/57g)CreamTopicalOlen Cosmetics Corporation2012-07-172013-07-08US flag
BabySpa Shea Butter DiaperZinc oxide (120 mg/1mL)CreamTopicalExpro3, Llc2012-07-18Not applicableUS flag
BacminZinc oxide (22.5 mg/1) + Ascorbic acid (500 mg/1) + Biotin (150 ug/1) + Chromium Cr-51 chloride (0.1 mg/1) + Cupric oxide (3 mg/1) + Cyanocobalamin (50 ug/1) + Ferrous fumarate (27 mg/1) + Flavone (50 mg/1) + Folic acid (1 mg/1) + Magnesium oxide (50 mg/1) + Manganese gluconate (5 mg/1) + Nicotinamide (100 mg/1) + Calcium pantothenate (25 mg/1) + Pyridoxine hydrochloride (25 mg/1) + Riboflavin (20 mg/1) + Selenomethionine (50 ug/1) + Thiamine mononitrate (20 mg/1) + Vitamin A acetate (2000 [iU]/1) + alpha-Tocopherol acetate (30 [iU]/1)Tablet, coatedOralMarnel Pharmaceuticals, Llc2000-04-01Not applicableUS flag
Bal-Care DHAZinc oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2850 [iU]/1) + Calcium carbonate (219 mg/1) + Cholecalciferol (840 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (.012 mg/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic acid (1 mg/1) + Iodine (.223 mg/1) + Iron sucrose (1.35 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (430 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (25.65 mg/1) + Thiamine mononitrate (1.8 mg/1)KitOralPru Gen Pharmaceuticals2012-05-01Not applicableUS flag
Bal-Care DHA EssentialZinc oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2850 [iU]/1) + Calcium carbonate (219 mg/1) + Cholecalciferol (840 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (.012 mg/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic acid (1 mg/1) + Iodine (.223 mg/1) + Iron sucrose (1.35 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (374 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (25.65 mg/1) + Thiamine mononitrate (1.8 mg/1)KitOralPru Gen Pharmaceuticals2012-05-01Not applicableUS flag
C-Nate DHAZinc oxide (20 mg/1) + Ascorbic acid (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cupric sulfate pentahydrate (1 mg/1) + Cyanocobalamin (15 ug/1) + Ferrous fumarate (28 mg/1) + Folic acid (1 mg/1) + Magnesium (30 mg/1) + Omega-3 fatty acids (200 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (3 mg/1) + Thiamine mononitrate (3 mg/1) + Vitamin E (30 [iU]/1)Capsule, gelatin coatedOralCenturion Labs, LLC2013-01-01Not applicableUS flag
Cavan AlphaZinc oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (3000 [iU]/1) + Calcium carbonate (230 mg/1) + Cholecalciferol (800 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic acid (1 mg/1) + Iodine (220 ug/1) + Iron (27 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (300 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Thiamine mononitrate (1.8 mg/1)KitOralSeton Pharmaceuticals2010-07-012013-09-30US flag

Categories

ATC Codes
C05AX04 — Zinc preparations
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as transition metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen is a transition metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Transition metal organides
Sub Class
Transition metal oxides
Direct Parent
Transition metal oxides
Alternative Parents
Inorganic salts / Inorganic oxides
Substituents
Inorganic oxide / Inorganic salt / Transition metal oxide
Molecular Framework
Not Available
External Descriptors
zinc molecular entity (CHEBI:36560)

Chemical Identifiers

UNII
SOI2LOH54Z
CAS number
1314-13-2
InChI Key
XLOMVQKBTHCTTD-UHFFFAOYSA-N
InChI
InChI=1S/O.Zn
IUPAC Name
oxozinc
SMILES
O=[Zn]

References

General References
  1. Derry JE, McLean WM, Freeman JB: A study of the percutaneous absorption from topically applied zinc oxide ointment. JPEN J Parenter Enteral Nutr. 1983 Mar-Apr;7(2):131-5. [PubMed:6406699]
  2. MSDS [Link]
  3. product info [Link]
KEGG Drug
D01170
PubChem Compound
14806
PubChem Substance
310265203
ChemSpider
14122
RxNav
11423
ChEBI
36560
ChEMBL
CHEMBL1201128
Wikipedia
Zinc_oxide
AHFS Codes
  • 84:24.12 — Basic Ointments and Protectants
  • 84:24.16 — Basic Powders and Demulcents
  • 84:80.00 — Sunscreen Agents
FDA label
Download (112 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentCesarean Section Complications / Postoperative Wound Infection / Satisfaction / Wound Breakdown / Wound Infections1
4CompletedTreatmentDiabetic Macular Edema (DME)1
4CompletedTreatmentDiaper Dermatitis1
4CompletedTreatmentDiaper Rash1
4CompletedTreatmentHyperpigmentation1
4CompletedTreatmentMelasma1
4CompletedTreatmentPain1
4CompletedTreatmentPressure Ulcers / Spinal Cord Injuries (SCI)1
3CompletedTreatmentIncontinence Associated Dermatitis / Incontinence-associated Dermatitis1
2CompletedTreatmentDentoalveolar Abscess1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
EmulsionTopical
LotionTopical20 mg/1mL
StickTopical87 mg/1g
Aerosol, sprayTopical120 mg/1mL
LotionTopical33.18 g/177mL
LotionTopical8.25 g/44mL
Cream; kitTopical
LotionTopical144 mg/1mL
CreamTopical4.97 g/100mL
EmulsionTopical1 g/100mL
EmulsionTopical3.3 g/100mL
LiquidTopical200 mg/100g
SolutionTopical1 g/100mL
SuspensionTopical3 g/100mL
CreamTopical140 mg/1mL
OilTopical220 mg/1mL
CreamTopical12 mg/100mL
Capsule, liquid filledOral
GelTopical5 mg/100mL
LotionTopical17 g/100g
CreamTopical100 mg/1mL
SuspensionTopical6.67 g/100mL
CreamTopical5.5 g/100g
StickTopical5.5 g/100g
LotionTopical0.1365 mg/1mL
CreamTopical13.5 g/100g
LotionTopical22.5 g/100g
CreamTopical17.5 g/100g
StickTopical4.14 g/18.4g
StickTopical11 g/100g
LotionTopical225 mg/1mL
PowderTopical5 g/100g
PowderTopical9.1 g/100g
LotionTopical20 g/100mL
SuspensionOral70000 IU/g
LipstickTopical8 g/100g
EmulsionTopical10 g/100mL
PatchCutaneous; Topical; Transdermal
SprayTopical10 g/99g
LotionTopical15 g/100mL
CreamTopical21 g/100g
LotionTopical8.5 g/100g
CreamTopical130 mg/1g
CreamTopical160 mg/1g
StickTopical192 mg/1g
CreamTopical200 mg/1mL
CreamTopical17.1 g/57g
CreamTopical10 g/10g
CreamTopical17 g/100g
OintmentTopical130 g/1g
CreamTopical16.51 g/127g
CreamTopical23.8 g/85g
CreamTopical2.75 g/11g
LotionTopical18 g/100g
CreamTopical0.75 g/60mL
CreamTopical150 mg/1g
OintmentTopical16 mL/100mL
OintmentTopical16 g/100g
CreamTopical16 g/100g
CreamTopical2.2727 g
CreamTopical120 mg/1mL
OintmentTopical1 g
LotionTopical12 g/100mL
LotionTopical14 g/100mL
KitTopical10 g/100mL
CreamTopical18.75 g/100mL
StickTopical8 g/100g
StickTopical8.0 g/100g
CreamTopical20 g/100mL
LotionTopical20.0 g/100mL
StickTopical22.5 g/100g
OintmentTopical18.75 mL/100mL
CreamTopical22.5 g/100mL
LotionTopical10.55 g/100mL
CreamTopical10 g/100mL
CreamTopical10.0 g/100mL
CreamTopical0.113 g/1g
CreamTopical.113 g/1g
PoulticeTopical
PowderTopical20 g/100g
CreamTopical12 %
CreamTopical210 mg/1mL
CreamTopical5.0016 g/100mL
StickTopical15.4 g/100g
EmulsionTopical19 g/100mL
LipstickTopical8.05 g/100g
LotionTopical140 mg/1mL
LotionTopical149.6 mg/1mL
LotionTopical19 g/100mL
CreamTopical17 mL/100mL
OintmentTopical0.10 g/1g
Ointment6 g/100g
LotionTopical19.7 g/100mL
Spray, suspensionTopical
LotionTopical18 g/100mL
CreamTopical1 g
CreamTopical15.25 g/100g
StickTopical20 mg/1g
CreamTopical34 g/85g
KitTopical19 g/100mL
OintmentTopical0.15 g/1g
OintmentTopical17.75 g/71g
CreamTopical16 g/113g
CreamTopical40 g/113g
OintmentTopical16 g/113g
LipstickTopical15 g/100g
LotionTopical0.6375 g/4.25g
CreamTopical14.4 g/100mL
StickTopical20 g/100g
LiquidTopical10 g/100mL
SprayTopical4 g/100g
PasteTopical45.2 g/113g
CreamTopical14.69 g/113g
SuspensionTopical0.2325 g
LotionTopical0.06 g
LotionTopical8 g
Tablet, coatedOral1188 mg
CreamTopical12 g/100g
CreamTopical16 g/70mL
CreamTopical120 mg/1g
SuppositoryRectal
SolutionTopical
StickTopical101 mg/1g
CreamTopical175 mg/1mL
LotionTopical145.7 mg/1mL
LotionTopical134.5 mg/1mL
CreamTopical12 g
LotionTopical
CreamTopical20 mg/100mL
CreamTopical220 mg/1mL
LotionTopical120 mg/1mL
CreamTopical
OintmentTopical2.5 mg/1g
CreamTopical185 mg/1g
KitTopical
LotionTopical150 mg/1mL
LotionTopical250.19 mg/1mL
StickTopical200 mg/1g
OintmentTopical0.4 g/1g
Aerosol, foamTopical
LotionTopical200 mg/1g
OintmentTopical13.0 kg/100kg
OintmentTopical13.0 kg/1g
CreamTopical10 g
CreamTopical10000000 millions
OintmentTopical40 g
PasteTopical200 mg/1g
OintmentTopical18 mg/1g
CreamTopical14.7 g/113g
CreamTopical0.013 g/1g
LotionTopical66 mg/1mL
LotionTopical10 g/100g
LotionTopical17.5 g/100g
CreamTopical12.5 g/100g
CreamTopical.135 mg/1g
LotionTopical160 mg/1mL
OintmentTopical2.5 g/25g
CreamTopical0.9 g/100mL
CreamTopical5.0 g/100g
LotionTopical95 mg/1mL
CreamTopical95 mg/1mL
CreamTopical152.5 mg/1g
CreamTopical12 g/100mL
PasteTopical400 mg/1g
OintmentTopical132.1 mg/1g
OintmentTopical40 g/100g
OintmentTopical21.76 g/100g
CreamTopical0.1 g/1g
CreamTopical0.113 kg/1g
CreamTopical0.13 g/1g
CreamTopical0.40 g/1g
OintmentTopical.1 g/1g
PasteTopical532 mg/1g
OintmentTopical0.2 g/1g
CreamTopical15 g/100mL
CreamTopical19 g/100mL
OintmentTopical14 g/100g
CreamTopical4.9 g/100g
CreamTopical96 mg/1g
OintmentTopical
OintmentTopical30 g/100g
Ointment1 g/100g
OintmentTopical100 mg/1g
SprayTopical10 g/100g
LiquidCutaneous
GelTopical100 mg/1mL
OintmentTopical65 mg/1g
OintmentRectal
OintmentTopical10 g/100g
CreamTopical0.01248 g/1g
CreamTopical4.9004028 g/100mL
LotionTopical2 g/120g
LotionTopical20 mg/100mL
LotionTopical170 mg/1mL
OintmentTopical250 mg/1g
OintmentTopical19 g/100g
CreamTopical215 mg/1g
CreamTopical24 g/100mL
OintmentTopical21 g/100g
PowderTopical15.004 g/100g
LotionTopical22 g/100g
LotionTopical25 g/100mL
LiquidTopical25 g/100mL
CreamTopical9.8 g/100mL
CreamTopical13.8 g/100mL
PowderTopical
CreamTopical75 g/1000g
AerosolTopical
CreamTopical225 mg/100mL
StickTopical0.4 g/4g
CreamTopical59.02 g/454g
CreamTopical181.6 g/454g
CreamTopical216 mg/1mL
CreamTopical20 mL/100mL
EmulsionTopical1.1 g/10g
LotionTopical107 mg/1mL
LotionTopical22.00 g/100mL
LotionTopical100 mg/1mL
CreamTopical163.2 mg/1mL
CreamTopical177 mg/1mL
LotionTopical13.6 g/100mL
CreamTopical168 mg/1mL
CreamTopical101 mg/1mL
LotionTopical19 g/100g
PatchTopical
LiquidTopical13.8 g/100mL
PatchTopical8.3 g/100g
CreamTopical25 mL/100mL
LotionTopical6.05 g/30mL
CreamTopical0.125 mL/1mL
LiquidTopical0.65 mg/130mL
PasteTopical200 mg/1mL
CreamTopical189 mg/1g
Capsule, delayed releaseOral0.6 mg
CreamTopical125 mg/1mL
CreamTopical190 mg/1g
PowderTopical0.02 g/1g
StickCutaneous
CreamTopical0.10 g/1g
CreamTopical13 mg/1g
PasteOral400 mg/1g
CreamTopical1.92 g/100mL
LotionTopical15.2 g/100mL
CreamTopical53.5 mg
CreamTopical5.35 %
GelTopical0.025 mg/100mL
LiquidTopical160 mg/1mL
LotionTopical25 g/100g
OintmentTopical0.4 g
OintmentRectal50 mg/1g
LotionTopical9.3 g/100mL
Spray, suspensionTopical12 g/100mL
CreamTopical0.03 g/1mL
PowderTopical0.0192 g/1g
PowderTopical0.0291 g/1g
LotionTopical13.5 g/100g
PasteTopical
CreamTopical110 g/1000g
Tablet, coatedOral
CreamTopical14.5 mg/1mL
OintmentTopical1.5 g
PowderTopical24.5 g/100g
LiquidTopical1.6 g/100g
CreamTopical0.07 g/1g
CreamTopical0.0192 g/1g
LiquidTopical0.02 g/1g
KitTopical130 mg/1g
PowderTopical100 mg/1g
Cream, augmentedTopical
LotionTopical16 g
LotionTopical17 g/100mL
SuspensionTopical8 g
OintmentTopical10 mL/100mL
CreamTopical20.2 g/100g
SuspensionOral15 g
OintmentTopical250 g/1000g
LotionTopical15 g/100g
CreamTopical16.96 mg/80mL
LotionTopical0.0157 g/1mL
LotionTopical0.48 g/30mL
LiquidTopical.016 g/1mL
LiquidTopical0.016 g/1mL
Lotion / shampooTopical
CreamTopical4 g/10g
CreamTopical9.45 mg/1mL
CreamTopical6.8 g/100mL
CreamTopical170 mg/1g
OintmentTopical113.6 g/284g
CreamTopical3.8 g/100g
OintmentTopical3.8 g/100g
LotionTopical30 g/150g
StickTopical10.5 g/100g
StickTopical15.45 g/100g
StickTopical8.55 g/100g
LipstickTopical105 mg/1mL
LiquidTopical66 mg/1mL
LipstickTopical
LotionTopical7.9 mg/100mL
SuspensionTopical1 g/100mL
LotionTopical204 mg/1mL
CreamTopical14 g/100mL
SuspensionTopical
OintmentTopical18 g/100g
CreamTopical0.0098 g/1g
CreamTopical400 mg/1g
OintmentRectal; Topical
SuppositoryRectal1.7 g/1
CreamTopical50 mg/1mL
DressingTopical19.8 g/165g
DressingTopical24.6 g/205g
StickTopical
GelTopical
OintmentTopical96 mg/1g
OintmentTopical9.6 g/100g
CreamTopical1.8 g/100g
PasteTopical40 g/100g
OintmentTopical8 g
PlasterTopical
StickTopical0.34 g/4.25g
LotionTopical147 mg/1mL
LotionTopical0.25 mg/1mg
LotionTopical22.8 g/100mL
CreamTopical50.0 mg/1mL
LipstickTopical80 mg/1g
PowderTopical127 mg/1g
Aerosol, sprayTopical20.5 g/100g
StickTopical17 g/100g
CreamTopical22400 mg/118.3mL
CreamTopical24 mg/1g
CreamCutaneous3.5 mL/50mL
LotionTopical175 mg/1mL
CreamTopical105 mg/1mL
LotionTopical19.5 g/100g
Tablet, chewableOral
PasteTopical100000 IU/g
CreamTopical9.9 g/100g
SprayTopical120 mg/1mL
LotionTopical240 mg/1mL
LotionTopical8.3 g/83g
LotionTopical5.5 g/55g
CreamTopical7 g/100mL
LotionTopical21 g/100mL
LotionTopical13.5 g/100mL
LiquidTopical16.1 g/100mL
LiquidTopical20.5 g/100mL
StickTopical21.8 g/100g
Ointment100000 IU/g
PowderCutaneous
SprayTopical3 g/100mL
Cream7.5 g/100g
Capsule, liquid filledOral0.6 mg
LotionTopical5.625 g/30mL
CreamTopical189 mg/1mL
CreamTopical7.85 g/50mL
LotionTopical24 g/68mL
CreamTopical24.96 g/100g
LotionTopical22 g/100mL
OintmentTopical8.8 g/88mL
LotionCutaneous
CreamTopical2 g
LotionTopical182.4 mg/1mL
LotionTopical216 mg/1mL
LotionTopical182 mg/1mL
StickTopical216 mg/1g
LotionTopical8.5 g/100mL
GelTopical20 g/100g
OintmentTopical2 g
LotionTopical17.5 g/100mL
CreamTopical.12 mL/1mL
Kit; lotionTopical
LotionTopical185 mg/1g
StickTopical10 g/100g
StickTopical5 g/100g
Ointment
KitTopical175 mg/1mL
CapsuleOral
StickTopical5.7 g/100g
CreamTopical17 g/100mL
LipstickTopical10 g/100g
Capsule, delayed releaseOral150 mg
CreamTopical114 mg/1mL
OintmentTopical0.08 g/56g
CreamTopical250 mg/1g
PasteTopical20 g
PasteTopical25 g
PasteTopical25 g/100g
LotionTopical
CreamTopical225 mg/1mL
CreamTopical2.4 g/0.259mL
OintmentTopical0.038 g/1g
CreamTopical60 g/1000g
LotionTopical0.13 mg/2.5mL
CreamCutaneous
LipstickTopical10.5 g/100g
PowderTopical24.7 g/100g
CreamTopical20 g/100g
OintmentTopical20 g/100g
Tablet, film coatedOral
GelTopical110 mg/1mL
PowderTopical250 mg/1g
CreamTopical5 g/1mL
CreamTopical210 mg/1g
CreamTopical7.5 g/100g
LotionTopical1 g/5g
CreamTopical5 g
LiquidTopical0.0098 g/1mL
LiquidTopical76 mg/1mL
SalveTopical20 g/100g
CreamTopical15 g/100g
LotionTopical7.5 mL/100mL
CreamTopical1.6 g/20mL
CreamTopical13 g/100g
CreamTopical15.5 g/100g
Cream20 g/100g
CreamTopical4.9 g/100mL
SprayTopical
OintmentTopical.20 g/1g
CreamTopical18.5 g/100g
LotionTopical250 mg/1g
StickTopical250 mg/1g
StickTopical227.5 mg/1g
CreamTopical230 mg/1mL
LotionTopical230 mg/1g
CreamTopical227.5 mg/1g
TabletOral
CreamTopical49.5 mg/1g
KitTopical4.95 mg/3g
LotionTopical49.5 mg/1mL
CreamTopical4.45 g/100g
CreamTopical49 mg/1g
CreamTopical25 g/100mL
DressingTopical
PasteTopical
PasteTopical20 g/100g
DressingTopical25 g/1
CreamTopical13 g/100mL
CreamTopical0.0686 mg/1g
PasteTopical220 mg/1g
OintmentTopical400 mg/1g
CreamTopical.9 mL/30mL
StickTopical35 mg/1g
CreamTopical8 g/90mL
CreamTopical0.26 g/1.54g
CreamTopical150 mg/1mL
PlasterTopical
LotionTopical228 mg/1mL
CreamTopical2000 mg
LotionTopical0.75 g/5mL
PowderTopical18 g/100g
Capsule, gelatin coatedOral
CreamTopical306.1 mg/1g
CreamTopical100 mg/1g
CreamTopical224 mg/1g
Aerosol, foamTopical140 mg/1mL
PowderTopical12 mg/0.1g
PowderTopical12 mg/100mg
CreamTopical11.6 mg/100mL
CreamTopical21 g/100mL
CreamTopical40 g/100g
PowderTopical
Cream500 mg/100g
LotionTopical19 g/142g
LotionTopical25 g/142g
OintmentTopical25 mg/100mg
PasteTopical12.5 g/100g
GelTopical10 g/100g
LipstickTopical0.462 g/4.62g
LotionTopical23.7 g/118.294g
OintmentTopical0.085 g/1g
StickTopical1.14 g/6.8g
OintmentTopical55 mg/1g
LipstickTopical65 mg/1g
CreamTopical.0702 mg/1g
LotionTopical22.75 g/100g
CreamTopical200 mg/1g
CreamTopical11 g/100mL
CreamTopical223 mg/1g
OintmentRectal3.5 g
CreamTopical10.8 g/96g
CreamTopical2.94 g/28g
CreamTopical.15 g/1g
LotionTopical20 g/100g
StickTopical3.06 g/17g
LotionTopical227 mg/1mL
CreamTopical186 mg/1mL
LotionTopical2495 g/501mL
StickTopical225 mg/1g
LotionTopical220 mg/1mL
StickTopical220 mg/1g
Aerosol, sprayTopical
KitTopical12 g/100mL
LiquidTopical8.82 g/90mL
LotionTopical16 g/100mL
SpongeTopical
SprayTopical140 mg/1mL
StickTopical80 mg/1g
StickTopical190 mg/1g
CreamTopical220 mg/1g
SprayTopical12 g/100mL
StickTopical17 g/100mL
GelTopical186 mg/1mL
CreamTopical190 mg/1mL
CreamTopical170 mg/1mL
CreamTopical43.4 g/177mL
CreamTopical28.9 g/118mL
CreamTopical25 g/100g
Cream5 g/100g
LiquidTopical50 mg/1mL
LotionTopical1 g/1g
LotionTopical134.4 mg/1mL
PowderTopical225 mg/1g
LotionTopical4.5 g/30mL
StickTopical21 g/100g
OilTopical20 g/100g
OintmentTopical20 g/84g
OintmentTopical22 g/100g
OintmentTopical25 g/100g
OintmentTopical50 g/100g
LotionTopical12.9 mL/52mL
LotionTopical1.24 mL/5mL
LotionTopical32.3 mL/130mL
LipstickTopical18 g/100g
CreamTopical882.7 mg/9.1g
Capsule, liquid filledOral1 mg
StickTopical24.5 g/100g
LotionTopical30 mg/1mL
PowderTopical12 g/100g
PowderTopical16 g/100g
OintmentTopical9 g/75g
SalveTopical
LotionTopical0.15 g/1g
LotionTopical100 ml
LotionTopical10 g/100mL
StickTopical200 ug/1g
LotionTopical200 mg/1mL
StickTopical105 ug/1g
StickTopical75 mg/1g
CreamTopical176.7 mg/1g
CreamTopical10 g/100g
CreamTopical0.12 g/1g
CreamTopical0.2 g/1g
SprayTopical25 g/100g
CreamTopical1.15 g/40mL
StickTopical22 g/100g
SprayTopical15 g/100g
LotionTopical20.5 g/100g
LotionTopical130 mg/1mL
PasteTopical12.8 g/100g
LotionTopical20 mL/100mL
SprayTopical24 mL/120mL
CreamTopical10 mL/50mL
CreamTopical0.135 mg/1g
OintmentTopical25 g
OintmentTopical0.5 g
PasteTopical5 mg/1cm2
CreamTopical.07 g/1g
OintmentTopical13.0 g/100g
OintmentTopical40.0 g/100g
LotionTopical6.87 g/34.35g
Tablet, chewableOral5000 IU
CreamTopical6.00 g/50mL
Capsule, liquid filledOral25 mg
PasteTopical125 mg/1g
PowderTopical0.69 g/3g
KitOral
PowderTopical2 g/100g
OintmentTopical0.40 g/1g
CreamTopical24 g/100g
PowderTopical24 g/100g
LotionTopical146 mg/1mL
CreamTopical14 g/100g
ClothTopical20 g/100g
LotionTopical190 mg/1mL
LotionTopical129.6 mg/1mL
LotionTopical122.4 mg/1mL
LotionTopical132 mg/1mL
LotionTopical135.6 mg/1mL
LotionTopical127 mg/1mL
StickTopical150 mg/1g
StickTopical125 mg/1g
LotionTopical12 mg/1mL
OintmentTopical0.5 g/100g
Cream
StickTopical7.6 g/100g
StickTopical6.5 g/100g
LotionTopical210 mg/1mL
CreamTopical1.96 g/100g
LiquidTopical
CreamTopical22 g/100g
LotionTopical8 g/100g
LotionTopical11 g/90g
LotionTopical22 g/90g
CreamTopical
CreamTopical0.2 kg/1kg
LotionTopical12.5 g/100g
Ointment15 g/100g
OintmentTopical.2 g/1g
OintmentTopical1.8 g/100g
OintmentTopical160 mg/1g
OintmentTopical200 mg/1g
PowderTopical30 g
Cream10 g/100g
Cream7 g/100g
OintmentTopical
Cream24.5 g/100g
Cream25 g/100g
PasteTopical10 g/100g
PasteTopical21 g/100g
PasteTopical25.93 g/100g
Ointment20 g/100g
PasteTopical50 g/100g
PasteTopical8 g/100g
LotionTopical13 g/100mL
LiquidNot applicable50 kg/100kg
CreamTopical186 mg/1g
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)Region
US8147852No2012-04-032028-03-30US flag
Additional Data Available
  • Filed On
    Filed On

    The date on which a patent was filed with the relevant government.

    Learn more

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-0.2ChemAxon
pKa (Strongest Basic)-5.7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area17.07 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity1.44 m3·mol-1ChemAxon
Polarizability3 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created on November 17, 2015 10:38 / Updated on October 26, 2020 22:41

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