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Apremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigationalApremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Apremilast G.L. 30 mg-FilmtablettenErythromycin
go.drugbank.com/drugs/DB00199ApprovedInvestigationalVet approvedErythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spi...
Mixtures: EFASOL GEL, ISOFACE GELCategories: P-glycoprotein inhibitors, P-glycoprotein substratesLoteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedLoteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, sup...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Lotemax GelGanciclovir
go.drugbank.com/drugs/DB01004ApprovedInvestigationalAn acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Products: VIRGAN EYE GEL 1.5 mg/g, VIRGAN® GEL OFTALMICOBromazepam
go.drugbank.com/drugs/DB01558ApprovedIllicitOne of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: BROMAZEPAM N&P, Bromazepam G.L. 3 mg - FilmtablettenCarbamide peroxide
go.drugbank.com/drugs/DB11129ApprovedInvestigationalSome adverse effects of carbamide peroxide as a dental bleaching agent include dentin sensitivity and/or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use.
Products: Select Brand Earwax Removal DropsIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigationalIbuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in ...
Mixtures: PAX MAX GEL®, NEXT GL GENOMMA LAB®Categories: P-glycoprotein inhibitors, P-glycoprotein substratesDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]
Mixtures: Cosopt PF, Cosopt PFCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesVenlafaxine
go.drugbank.com/drugs/DB00285ApprovedInvestigationalVenlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Venlafaxin G.L. 75 mg - Tabletten, Venlafaxin G.L. 25 mg - TablettenMethoxsalen
go.drugbank.com/drugs/DB00553ApprovedInvestigationalA naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 InhibitorsProducts: METOXSALENE G.L. PHARMA