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Mexazolam
go.drugbank.com/drugs/DB15489InvestigationalMexazolam (CS-386) is a benzodiazepine indicated for the treatment of anxiety with or without psychoneurotic conditions. Mexazolam's structure is similar to that of other benzodiazepines such as oxazolam and cloxazolam. The use of benzod...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFennel
go.drugbank.com/drugs/DB15615ApprovedCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP2E1 InhibitorsUlotaront
go.drugbank.com/drugs/DB15665InvestigationalSEP-363856 is a novel psychotropic drug being investigated for the treatment of schizophrenia. Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–assoc...
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesUmbilical Cord Blood Hematopoietic Stem Cells
go.drugbank.com/drugs/DB15723InvestigationalCord blood transplants have been used to treat conditions from aplastic anemia, B-thalassemia, X-linked lymphoproliferative syndrome, Hunter’s syndrome, acute lymphoid leukemia, chronic myeloid leukemia
Fenchone
go.drugbank.com/drugs/DB15918InvestigationalSynonyms: DL-FenchoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesGarlic oil
go.drugbank.com/drugs/DB15989InvestigationalCategories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsSotagliflozin
go.drugbank.com/drugs/DB12713ApprovedInvestigationalSotagliflozin is a dual inhibitor of SGLT1 and SGLT2, the first of its kind, which is approved for use in the EU, in combination with insulin, to improve glycemic control in patients with type 1 diabetes mellitus (T1DM) and a BMI ≥27 kg/...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesN-omega-nitro-L-arginine methyl ester
go.drugbank.com/drugs/DB12750InvestigationalL-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
Synonyms: L-NAME, NG-nitro-L-arginine methyl esterLefamulin
go.drugbank.com/drugs/DB12825ApprovedLefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia. A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus. Lefamulin is av...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTrofosfamide
go.drugbank.com/drugs/DB12902InvestigationalTrofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates