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Displaying results 1891 - 1900 of 10000 in total
  1. Drug

    Zotepine

    go.drugbank.com/drugs/DB09225
    ApprovedWithdrawn

    In the EMA, by 2015 it was under pharmacovigilance studies for the potential treatment of acute renal failure.[L1314] … [A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's.[A31857] Zotepine was never approved by the FDA.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  2. Drug

    Inositol nicotinate

    go.drugbank.com/drugs/DB08949
    ApprovedWithdrawn

    Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. … Inositol nicotinate is prescribed in Europe under the name Hexopal as a symptomatic treatment for severe intermittent claudication and Raynaud’s phenomenon.

    Mixtures: Tricare Prenatal DHA One Rx Multivitamin
  3. Drug

    Cytidine-5'-Monophosphate

    go.drugbank.com/drugs/DB03403
    Investigational

    A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.

    Salts: Cytidine 5'-Monophosphate Disodium Salt
  4. Drug

    Palovarotene

    go.drugbank.com/drugs/DB05467
    Approved

    [A244920] Palovarotene was approved for use in Canada in January 2022 for the management of heterotopic ossification (HO) in patients with FOP, representing the first global approval for any FOP therapy … [A244920] The ossification occurring as a result of FOP is insidious and cumulative and is provoked during flare-ups or in response to injury.

  5. Drug

    Hyoscyamine

    go.drugbank.com/drugs/DB00424
    ApprovedInvestigational

    [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties. … [L31548,L31553] Although hyoscyamine is marketed in the United States, it is not FDA approved.[L31548,L31553]

    Mixtures: UR N-C Urinary Antiseptic, Re-PB HyosCategories: Drugs for Functional Gastrointestinal Disorders
  6. Drug

    Fluvoxamine

    go.drugbank.com/drugs/DB00176
    ApprovedInvestigational

    Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. … It was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine.

    Categories: Antidepressive Agents Indicated for Depression, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: VERLIN TABLETAS X 50 MG
  7. Target

    Sequestosome-1

    go.drugbank.com/bio_entities/BE0014160
    TargetHumans

    cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport (PubMed:27368102, PubMed:33472082). … Molecular adapter required for selective macroautophagy (aggrephagy) by acting as a bridge between polyubiquitinated proteins and autophagosomes (PubMed:15340068, PubMed:15953362, PubMed:16286508, PubMed

    Synonyms: Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa
  8. Indication

    Salt-losing Androgenital syndrome

    go.drugbank.com/conditions/DBCOND0123106
    Drugs: Fludrocortisone
    Synonyms: Salt-losing Androgenital syndrome
  9. Drug

    Bebtelovimab

    go.drugbank.com/drugs/DB16755
    ApprovedWithdrawn

    in the US. … [L43827] On November 30, 2022, the EUA for bebtelovimab was officially withdrawn due to a lack of efficacy against Omicron subvariants, therefore bebtelovimab is no longer authorized for emergency use

    Categories: Approved Treatments for COVID-19
  10. Drug

    Ferric cation

    go.drugbank.com/drugs/DB13949
    ApprovedWithdrawn

    Non-haem iron in food is mainly in the ferric state, which is the insoluble form of iron, and must be reduced to the ferrous cation for absorption [T28]. … Ferric citrate (tetraferric tricitrate decahydrate) is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

    Mixtures: FERPLEX FOL, FERPLEX FOLSynonyms: Ferric ion, FE (III) ION