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Displaying results 1901 - 1910 of 10000 in total
  1. Drug

    Tenofovir alafenamide

    go.drugbank.com/drugs/DB09299
    ApprovedInvestigational

    Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil]. … [A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir disoproxil.

    Mixtures: Descovy® (emtricitabine 200 mg/ tenofovir alafenamide 10 mg) film-coated tablets, ODEFSEY® 200 MG - 25 MG - 25 MG TABLETAS RECUBIERTASCategories: Vitamin B Complex, Cytochrome P-450 Substrates
  2. Drug

    Peginterferon beta-1a

    go.drugbank.com/drugs/DB09122
    ApprovedInvestigational

    Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. … [A176474,L5792] Peginterferon beta-1a is an interferon therapy used for the management of relapsing forms of MS.

    Synonyms: PEG IFN-beta-1a, Peginterferon beta-1aMixtures: PLEGRİDY 63 MCG/0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1 ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML, PLEGRİDY 63 MCG/0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1 ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML
  3. Drug

    Bumetanide

    go.drugbank.com/drugs/DB00887
    ApprovedInvestigational

    Bumetanide is a sulfamyl diuretic.

    Mixtures: BURINEX TABLET 1 mg, BURINEX TABLET 1 mgCategories: Increased Diuresis at Loop of Henle
  4. Drug

    Eculizumab

    go.drugbank.com/drugs/DB01257
    ApprovedInvestigational

    [L6919,A2245] Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions. … Eculizumab is a monoclonal antibody that targets complement protein C5.

    Products: Bekemv 300 mg/30 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADET, ELİZARİA 300 MG/30 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET
  5. Drug

    Carfilzomib

    go.drugbank.com/drugs/DB08889
    ApprovedInvestigational

    Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor. … FDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple myeloma as monotherapy or combination therapy.[L39392]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: Kyprolis 10 mg IV İnfüzyonluk Çözelti Hazırlamak İçin Toz, 1 ADET, ANPROTSOM ® 60 MG
  6. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones [L1891]. … Due to its bifunctional properties, undecylenate is also used as a linking molecule to conjugate other biomolecules such as proteins. It serves as an acid moiety for anabolic steroid boldenone.

    Synonyms: 10-undecenoic acid, ácido 10-undecenoicoMixtures: FUNGECYL POUDRE, 100 GR, FUNGECYL POUDRE, 100 GR
  7. Drug

    Clopidogrel

    go.drugbank.com/drugs/DB00758
    ApprovedInvestigational

    Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. … L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI

    Mixtures: KLOGEL-A 75/100 MG KAPSUL, 30 ADET, KLOGEL-A 75/100 MG KAPSUL, 90 ADETCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  8. Drug

    Cobimetinib

    go.drugbank.com/drugs/DB05239
    ApprovedInvestigational

    Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: COTELLIC® (COBIMETINIB) 20 MG TABLETAS RECUBIERTAS, COTELLIC FILM-COATED TABLET 20 MG
  9. Drug

    Flunarizine

    go.drugbank.com/drugs/DB04841
    ApprovedInvestigational

    Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. … It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
  10. Drug

    DL-alpha tocopheryl acetate

    go.drugbank.com/drugs/DB14477
    Approved

    Mixtures: Folika-MG, A/o-26 - CapletCategories: Vitamin E