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Methylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalThe drug is of potential interest for the treatment of patients with Alzheimer's disease. … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: BLUMET 50 MG/5 ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN AMPUL ,1 AMPUL, BLUMET 100 MG/10 ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN AMPUL ,1 AMPULCariprazine
go.drugbank.com/drugs/DB06016ApprovedInvestigational[L40198] Cariprazine has been investigated in a variety of psychiatric disorders, including schizophrenia, bipolar disorders, and major depressive disorder. … [L41670] It is currently used to treat schizophrenia, and manic or mixed episodes and depressive episodes associated with bipolar I disorder.[L41655,L40198]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: SYMVENU 1.5 MG, SYMVENU 3.0 MGIvosidenib
go.drugbank.com/drugs/DB14568ApprovedInvestigationalof acute myeloid leukemia and cholangiocarcinoma. … [A248745] Ivosidenib was granted accelerated approval by the FDA in July 2018 for the treatment of relapsed of refractory acute myeloid leukemia in adults.
Minaprine
go.drugbank.com/drugs/DB00805ApprovedMinaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain. … Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigational[L32965] Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050 … Linezolid was initially approved in 2000 and was the first member of the oxazolidinone antibiotic class.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Zyvoxam 600 mg, LINEXA 600 MGHydroxyethyl cellulose
go.drugbank.com/drugs/DB11602ApprovedIt is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic
Categories: Compounds used in a research, industrial, or household settingAliskiren
go.drugbank.com/drugs/DB09026ApprovedInvestigationalAliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. … [L14018] Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in conjunction with other antihypertensive agents.[A203624]
Categories: Agents Acting on the Renin-Angiotensin SystemHomatropine methylbromide
go.drugbank.com/drugs/DB00725ApprovedHomatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. … Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics.
Crizotinib
go.drugbank.com/drugs/DB08865ApprovedInvestigationalCrizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic … Second- and third-generation ALK-tyrosine kinase-inhibitors have overcome many of the pharmacodynamic and genetic resistance mechanisms crizotinib is prone to.
Products: XALKORI®250 MG CÁPSULAS, XALKORI 200 MG KAPSUL, 60 ADETValaciclovir
go.drugbank.com/drugs/DB00577ApprovedInvestigationalThis class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900]. One major use of valacyclovir is the treatment of genital herpes episodes or outbreaks. … Valacyclovir is the L-valine ester of aciclovir. It is a member of the purine (guanine) nucleoside analog drug class [F3949].
Products: HETVAL 500 MG, VALACICLOVIR 1 G