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Nerandomilast
go.drugbank.com/drugs/DB18237ApprovedInvestigationalIt has one chiral center and is the R-stereoisomer.[L54126] On October 7, 2025, nerandomilast was approved as the first new treatment for idiopathic pulmonary fibrosis in more than a decade.
Nilotinib
go.drugbank.com/drugs/DB04868ApprovedInvestigationalNilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered si...
Hydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedIt is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid).
Sarilumab
go.drugbank.com/drugs/DB11767ApprovedInvestigational[A27262] Sarilumab was developed by Sanofi and Regeneron Pharmaceuticals, Inc; it was US FDA-approved in May 2017 and followed by EU approval in June 2017 for the treatment of moderate to severe rheumatoid
Arformoterol
go.drugbank.com/drugs/DB01274ApprovedIt works by relaxing muscles in the airways to improve breathing.
Toremifene
go.drugbank.com/drugs/DB00539ApprovedInvestigational, it also has antiestrogenic (estrogen-antagonist) activity on breast tissue. … [A256928] Toremifene possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and on bone tissue and it has weak estrogenic effects on uterine tissue, however
L-arginine
go.drugbank.com/drugs/DB17289ApprovedInvestigationalNutraceuticalMixtures: Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose InjecCladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigational[A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell
Rilzabrutinib
go.drugbank.com/drugs/DB17709ApprovedInvestigationalRilzabrutinib is thought to work by dual mechanisms of action in ITP: It attenuates macrophage (Fcγ receptor)-mediated platelet destruction and reduces the production of pathogenic autoantibodies.