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Profenamine
go.drugbank.com/drugs/DB00392ApprovedIt is sold under the trade name Parsitan in Canada.[L46812] In the US, the marketing of profenamine has been discontinued.[L46817] … Profenamine (also known as ethopropazine) is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat Parkinsonism.
Synonyms: N,N-diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine, N,N-diethyl-α-methyl-10H-phenothiazine-10-ethanamineDosulepin
go.drugbank.com/drugs/DB09167ApprovedInvestigationalIt is not FDA-approved due to low therpeutic index and significant toxicity in overdose. … Its hydrochloride form is a common active ingredient in different drug formulations.
Synonyms: (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amineBordetella pertussis pertactin antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10992ApprovedInvestigationalMixtures: Repevax Injektionssuspension in einer FertigspritzeTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigational[A253712] Tremelimumab was first approved by the FDA in October 2022 to be used in combination with [durvalumab] to treat hepatocellular carcinoma. … [A253717, L43652] Because CTLA-4 is an immune checkpoint that plays a vital role in regulating T cell-mediated immune response, tremelimumab is considered an immune checkpoint inhibitor, which is an emerging
Pholcodine
go.drugbank.com/drugs/DB09209ApprovedIllicit[A31742] Pholcodine is not prescribed in the United States where it is classed as a Schedule I drug. It is categorized as Class B drug in the UK and officially taken out of the shelves in 2008. … Pholcodine is not approved in Canada.
Bardoxolone
go.drugbank.com/drugs/DB12651InvestigationalIn contrast, Bardoxolone in normal cells induces protective antioxidant/anti-inflammatory responses. … Bardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors.
Carglumic acid
go.drugbank.com/drugs/DB06775ApprovedInvestigationalCarglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. … This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death.
Synonyms: N-Carbamylglutamate, N-Carbamyl-L-glutamateHaemagglutinin-strain A(H3N2)
go.drugbank.com/drugs/DB15475ApprovedInvestigationalMixtures: Afluria Tetra Injektionssuspension in einer FertigspritzeHaemagglutinin-strain A(H1N1)
go.drugbank.com/drugs/DB15476ApprovedInvestigationalMixtures: Afluria Tetra Injektionssuspension in einer FertigspritzeNurulimab
go.drugbank.com/drugs/DB18946InvestigationalNurulimab is under investigation in clinical trial NCT05732805 (A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-pd-1 Compared to Anti-pd-1 Monotherapy as First-line Treatment in