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Testosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationals Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector [L4659]. … The majority of the prescriptions written were for injectable (66%) and topical (32%) testosterone products. As recent as 1 October 2018, the US FDA approved Antares Pharma Inc.'
Mixtures: NOFERTYL® INYECTABLECategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesTegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawnin female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular event than the broader population. … Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein substratesSynonyms: 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidinePhentermine
go.drugbank.com/drugs/DB00191ApprovedIllicitInvestigational[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. … [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: TERFAMEX T, Adipex-PBetrixaban
go.drugbank.com/drugs/DB12364ApprovedBetrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [A7708]. … VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [A27287].
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamideSynthetic Conjugated Estrogens, B
go.drugbank.com/drugs/DB09318ApprovedHowever, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control … Synthetic conjugated estrogens, B tablets contain a blend of ten synthetic estrogenic substances.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: Estrogens, Conjugated Synthetic B, Synthetic Conjugated Estrogens, BCurcumin
go.drugbank.com/drugs/DB11672ApprovedInvestigationalCurcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in [Curcuma xanthorrhiza oil]. … Curcumin is under investigation for the treatment and supportive care of various clinical conditions including mucositis, rectal cancer, prostate cancer, chronic schizophrenia, and Mild Cognitive Impairment
Mixtures: Melittin Joint Soothing GeCategories: P-glycoprotein inhibitors, P-glycoprotein substratesSynthetic Conjugated Estrogens, A
go.drugbank.com/drugs/DB09317ApprovedHowever, once a woman stops ovulating there is a sharp decline in the production of progesterone and estradiol by the ovaries and a consequent fluctuation in LH and FSH due to a lack of feedback control … Prior to menopause, the primary source of estrogen is the ovarian follicle, which secretes 70-500 micrograms of estradiol daily, depending on the phase of the menstrual cycle.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: Estrogens, Conjugated Synthetic A, Synthetic Conjugated Estrogens, APizotifen
go.drugbank.com/drugs/DB06153ApprovedPizotifen belongs to the class of antamines and is related to [cyproheptadine].[A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. … Sandomigran is available in a number of countries but is not approved by the FDA nor EMA.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds, 1-RingProducts: Sandomigran DSVaricella zoster vaccine (recombinant)
go.drugbank.com/drugs/DB13924ApprovedInvestigationalThe main immunological component of Shingrix vaccine is glycoprotein E (gE), a protein found on the surface of varicella zoster virus (VZV). … Decades later, when the body's immune system weakens with age, VZV is able to reactivate and descend through the nerve cells to the surface of the skin where it causes a painful blistering rash.
Synonyms: gE recombinant Varicella zoster virus (VZV) glycoprotein E, gE: Recombinant Varicella Zoster Virus (VZV) glycoprotein ETeplizumab
go.drugbank.com/drugs/DB06606ApprovedInvestigational[A241480,A241500] Targeting T cells can be achieved through antibodies against the T cell receptor (TCR) component CD3. … Teplizumab (teplizumab-mzwv) is a humanized IgG1 kappa CD3-directed monoclonal antibody used to delay the onset of type 1 diabetes (T1D).