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Displaying results 1931 - 1940 of 2454 in total
  1. Drug

    Abametapir

    go.drugbank.com/drugs/DB11932
    Approved

    Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice. The life cycle of head lice (Pediculus capitis) is approximately 30 days, seven to twelve of which are spent as eggs laid on hair sh...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
  2. Drug

    Carboxyamidotriazole

    go.drugbank.com/drugs/DB11960
    Investigational

    Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    GDC-0623

    go.drugbank.com/drugs/DB11982
    Investigational

    GDC-0623 has been used in trials studying the treatment of Solid Cancers.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates
  4. Drug

    Benznidazole

    go.drugbank.com/drugs/DB11989
    ApprovedInvestigational

    Benznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017. It is the first treatment made available in the United States for Chagas disease.

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  5. Drug

    Diacerein

    go.drugbank.com/drugs/DB11994
    ApprovedInvestigationalWithdrawn

    Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea . Diacerein is und...

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  6. Drug

    Ditiocarb zinc

    go.drugbank.com/drugs/DB14193
    Approved

    Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen. Sensitivity to ditiocarb zinc may be identified with a clinical patch test.

    Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP2E1 Inhibitors
  7. Drug

    Hydrocortisone aceponate

    go.drugbank.com/drugs/DB14538
    InvestigationalVet approved

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers
  8. Drug

    Curcumin sulfate

    go.drugbank.com/drugs/DB14635
    Experimental

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2B6 Inhibitors
  9. Drug

    Prednisone acetate

    go.drugbank.com/drugs/DB14646
    ApprovedInvestigationalWithdrawn

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  10. Drug

    Clocortolone acetate

    go.drugbank.com/drugs/DB14652
    Experimental

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers