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Displaying results 1941 - 1950 of 10000 in total
  1. Drug

    Ribaxamase

    go.drugbank.com/drugs/DB16311
    Investigational

    Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).

  2. Drug

    Rinucumab

    go.drugbank.com/drugs/DB16313
    Investigational

    Rinucumab is under investigation in clinical trial NCT02418754 (Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-related Macular Degeneration (AMD)).

    Synonyms: Immunoglobulin g4, anti-(human platelet-derived growth factor receptor~) (human monoclonal regn2176 heavy chain), disulfide with human monoclonal regn2176 k-chain, dimer
  3. Drug

    S-777469

    go.drugbank.com/drugs/DB16321
    Investigational

    S-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis).

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Sepiapterin

    go.drugbank.com/drugs/DB16326
    ApprovedInvestigational

    Sepiapterin is a small molecule activator of phenylalanine hydroxylase (PAH) used to reduce phenyalanine levels in patients with phenylketonuria. … It is a natural precursor of the enzymatic co-factor tetrahydrobiopterin (BH4), which activates PAH and helps reduce blood phenylalanine levels by enhancing the conformational stability of misfolded PAH

    Categories: Heterocyclic Compounds, 2-RingSynonyms: L-sepiapterin
  5. Drug

    Simurosertib

    go.drugbank.com/drugs/DB16330
    Investigational

    Simurosertib is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one
  6. Drug

    Siremadlin

    go.drugbank.com/drugs/DB16331
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Sodelglitazar

    go.drugbank.com/drugs/DB16332
    Investigational

    Sodelglitazar is under investigation in clinical trial NCT00196989 (Study in People With Type 2 Diabetes).

  8. Drug

    Sonlicromanol

    go.drugbank.com/drugs/DB16333
    Investigational

    Sonlicromanol is under investigation in clinical trial NCT04165239 (The KHENERGYZE Study).

    Synonyms: (S)-6-Hydroxy-2,5,7,8-Tetramethyl-N-((R)-Piperidin-3-Yl)Chroman-2-CarboxamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    Sulopenem etzadroxil

    go.drugbank.com/drugs/DB16335
    ApprovedInvestigational

    Sulopenem etzadroxil is a prodrug of the penem antibacterial [sulopenem]. Like other beta-lactam antibacterials, it is a time-dependent inhibitor of bacterial cell wall synthesis.

  10. Drug

    Trastuzumab duocarmazine

    go.drugbank.com/drugs/DB16342
    Investigational

    Trastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens erbb2 (epidermal growth factor receptor 2, receptor tyrosineprotein kinase erbb-2, egfr2, her2, her-2, p185cerbb2, neu, cd340)), humanized monoclonal antibodyCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors