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Orlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalThe global prevalence of obesity is increasing rapidly. … Obesity-related complications lead to significant personal and economic burden by reducing quality of life and increasing the cost of healthcare.
Ketoprofen
go.drugbank.com/drugs/DB01009ApprovedInvestigationalVet approvedKetoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Mixtures: DOLFORT-DEProducts: Orudis E-50, Ketoprofen-EPotassium hydroxide
go.drugbank.com/drugs/DB11153ApprovedIt was determined that topical KOH solution was found to be a safe and effective treatment of plane warts [L1941]. … Potassium hydroxide is also a precursor to other potassium compounds. Potassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent.
Synonyms: hydroxyde de potassiumClomipramine
go.drugbank.com/drugs/DB01242ApprovedInvestigationalVet approvedThe antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … Clomipramine is rapidly absorbed from the gastrointestinal tract and demethylated in the liver to its primary active metabolite, desmethylclomipramine.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AntagonistsProducts: ANAFRANIL® RETARD 75 MG TABLETAS RECUBIERTAS DE LIBERACION PROLONGADASulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigational[A255582] Sulfasalazine fell out of favor as the drug of choice for RA due to poorly designed clinical trials in 1950 but regained interest from the clinical community in the late 1970. … [A255582] Compared to the first line treatment of RA like methotrexate, sulfasalazine is almost as efficacious as methotrexate although with slightly less tolerability.
Products: SARIDINE - ERemestemcel-L
go.drugbank.com/drugs/DB13973ApprovedInvestigationalWithdrawnThe mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells … It is estimated that the patients with the most severe forms of refractory aGvHD that do not respond to steroid therapy have expected one-year survival rates of only 5% to 30% [L11022].
Olodaterol
go.drugbank.com/drugs/DB09080ApprovedInvestigationalActivation of the receptor stimulates an associated G protein which then activates adenylate cyclase, catalyzing the formation of cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA). … Despite similarities in symptoms, olodaterol is not indicated for the treatment of acute exacerbations of COPD or for the treatment of asthma.
Categories: Agents to Treat Airway Disease, Adrenergic beta-1 Receptor AgonistsProducts: SPIOLTO® RESPIMAT® RE-USABLE SOLUTION FOR INHALATION 2.5 MICROGRAM / 2.5 MICROGRAMEvening primrose oil
go.drugbank.com/drugs/DB11358ApprovedNutraceutical[A33131] Evening primrose oil has been filled for the FDA by Humanetics Corporation on April 2000 to be a new dietary ingredient but its current status is "Inadequate basis for expectation of safety". … [L2845] By Health Canada, evening primrose oil is approved in over-the-counter combination dietary supplements.[L1113] By the EMA, evening primrose oil is approved in herbal preparations.[L2851]
Mixtures: PRIM E CAPSULE, Evening Primrose Oil With Vitamin EInterferon alfa-2b
go.drugbank.com/drugs/DB00105ApprovedInvestigationalInterferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles i...
Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules)Bendroflumethiazide
go.drugbank.com/drugs/DB00436ApprovedInvestigational(From Martindale, The Extra Pharmacopoeia, 30th ed, p810) … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders.