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Diphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalAt high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. … When diphenoxylate is used alone, it is classified as a Schedule II.
OSI-930
go.drugbank.com/drugs/DB05913InvestigationalOSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2).
Viloxazine
go.drugbank.com/drugs/DB09185ApprovedInvestigationalWithdrawnIt was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy.
Flunitrazepam
go.drugbank.com/drugs/DB01544ApprovedIllicitSome reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
Indalpine
go.drugbank.com/drugs/DB08953ApprovedWithdrawnIt was initially marketed by Pharmuka. … However, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported hematological effects caused by Indalpine, it was abruptly withdrawn from the US market.
Loteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedAs a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. … It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes
Exametazime
go.drugbank.com/drugs/DB11179ApprovedIt acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. … It is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous leukocytes.
Products: CERETEC ESTABILIZADO KIT DE 500 MICROGRAMOS PARA PREPARACIÓN RADIOFARMACÉUTICAMicrocrystalline cellulose
go.drugbank.com/drugs/DB14158ApprovedInvestigationalIt is the chief constituent of plant fibers, cotton being the purest natural form of the substance. … As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
Tazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalIt is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections.
Afamitresgene autoleucel
go.drugbank.com/drugs/DB18592ApprovedInvestigational[L51114] On August 2, 2024, the FDA granted the accelerated approval of afamitresgene autoleucel, making it the first FDA-approved TCR gene therapy and the first gene therapy for the treatment of synovial