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Displaying results 1951 - 1960 of 10000 in total
  1. Drug

    Candesartan

    go.drugbank.com/drugs/DB13919
    Investigational

    Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of [candesartan cilexetil].

    Synonyms: 2-ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acidMixtures: EUROPRES - D 16 MG / 12.5 MG TABLETA., โบล์เพรส 16 มิลลิกรัม พลัส
  2. Drug

    Gadoxetic acid

    go.drugbank.com/drugs/DB08884
    ApprovedInvestigational

    Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. … A263156] Gadoxetate is a unique gadolinium-based contrasting agent (GBCA) with both dynamic phase and hepatobiliary phase and thus has different pharmacokinetic and pharmacodynamic properties compared to

    Products: Primovist 0.25 mmol/ml Solution for injection, PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTION
  3. Drug

    Lindane

    go.drugbank.com/drugs/DB00431
    ApprovedWithdrawn

    In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical … Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment.

    Synonyms: (1r,2c,3t,4c,5c,6t)-1,2,3,4,5,6-hexachlorocyclohexane, (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexaneProducts: Hexit Shampoo 1.0%
  4. Drug

    Floxuridine

    go.drugbank.com/drugs/DB00322
    ApprovedInvestigational

    When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. … An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution.

    Synonyms: 5-FUdR, 5-FluorodeoxyuridineCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  5. Drug

    Flurandrenolide

    go.drugbank.com/drugs/DB00846
    Approved

    A corticosteroid used topically in the treatment of various skin disorders. It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive. (From Martindale, The Extra Pharmacopoeia, 30th ed, p...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Drenison Tape M 170 4mcg Sq Cm
  6. Drug

    Pacritinib

    go.drugbank.com/drugs/DB11697
    ApprovedInvestigational

    of both primary and secondary MF in patients with platelet counts < 50 x 10<sup>9</sup>/L. … [L40793] The underlying cause of primary MF is unknown, but secondary MF can arise in patients with a history of polycythemia vera or essential thrombocythemia.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Substrates
  7. Drug

    Cerebrolysin

    go.drugbank.com/drugs/DB16599
    Investigational

    Products: Ambotonin 215,2 mg/ml - parenterale Lösung Injektionslösung/Konzentrat zur Herstellung einer Infusionslösung
  8. Drug

    Kaolin

    go.drugbank.com/drugs/DB01575
    Approved

    Kaolin is a layered silicate mineral. Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. Until the early 1990s it was ...

    Mixtures: BIOGASTRIN TOZ, 60 G, Donnagel-MB SusProducts: Look At Me Mud Face Mask Mini Pack Lotus, Look At Me Mud Face Mask Mini Pack Aloe
  9. Drug

    Calcium polycarbophil

    go.drugbank.com/drugs/DB14684
    Approved

    Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali. … Polycarbophil is used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea.

    Products: Calcium Polycarbophil 625 mg
  10. Drug

    Xanomeline

    go.drugbank.com/drugs/DB15357
    ApprovedInvestigational

    discovered that M1 and M4 muscarinic acetylcholine receptors are highly expressed in brain regions that are implicated in cognition. … [A264514] Xanomeline is a muscarinic agonist that was approved for the treatment of schizophrenia by the FDA in September 2024, becoming the first approved treatment for schizophrenia to target muscarinic

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates