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Oplunofusp
go.drugbank.com/drugs/DB15313InvestigationalDAS-181 is under investigation in clinical trial NCT00527865 (Single Dose Escalating Study of DAS181 in Adults).
N-Acetyl-glucosamine thiazoline
go.drugbank.com/drugs/DB03747ExperimentalN-Acetyl-glucosamine thiazoline (NAG-thiazoline) is an analog of the oxazolinium bicyclic intermediate leading from N-acetylglucosamine to 1,6-anhydro-N-acetylmuramic acid.
Synonyms: N-Acetyl-glucosamine thiazoline, NAG-thiazolineNasoVAX
go.drugbank.com/drugs/DB15859InvestigationalThe compound has already shown to be tolerated with no adverse effects or fever in healthy individuals with a nearly 6-fold cellular immune response in comparison to an injectable vaccine[L16313].
Sirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigationalSirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria _Streptomyces hygroscopicus_, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: P-HYSPLANDaclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnThe human sequences were derived from the constant domains of human IgG1 and the variable framework regions of the Eu myeloma antibody.
Betibeglogene autotemcel
go.drugbank.com/drugs/DB16900ApprovedInvestigationalThe use of betibeglogene autotemcel is more effective in patients with β-thalassemia with residual β-globin synthesis (non-β<sup>0</sup>/β<sup>0</sup> genotype) compared to those with no detectable β-globin
Avibactam
go.drugbank.com/drugs/DB09060ApprovedInvestigationalAvibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in co...
Palbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigationalPalbociclib is a piperazine pyridopyrimidine that acts in the cell cycle machinery. It is a second generation cyclin-dependent kinase inhibitor selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmac...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesArticaine
go.drugbank.com/drugs/DB09009ApprovedInvestigationalArticaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Mixtures: Septanest N, Posicaine NAcetic acid
go.drugbank.com/drugs/DB03166ApprovedInvestigationalAcetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) ...
Mixtures: Fem pH, Acetate Buffer Ph 4.85