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Displaying results 1981 - 1990 of 10000 in total
  1. Drug

    Darexaban

    go.drugbank.com/drugs/DB12289
    Investigational

    Darexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.

    Categories: Factor Xa Inhibitors
  2. Drug

    Uracil mustard

    go.drugbank.com/drugs/DB00791
    Approved

    It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

    Synonyms: 5-N,N-bis(2-chloroethyl)aminouracil
  3. Drug

    Salsalate

    go.drugbank.com/drugs/DB01399
    ApprovedInvestigational

    In contrast to aspirin, salsalate causes no greater fecal gastrointestinal blood loss than placebo. … Salsalate is a nonsteroidal anti-inflammatory agent for oral administration.

  4. Drug

    Nabumetone

    go.drugbank.com/drugs/DB00461
    Approved

    [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite acting as a potent COX inhibitor similar in structure to [naproxen]. … Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).

    Mixtures: NuDroxiPAK N-500
  5. Drug

    Galsulfase

    go.drugbank.com/drugs/DB01279
    ApprovedInvestigational

    Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular

    Synonyms: N-acetylgalactosamine-4-sulfatase, recombinant human
  6. Drug

    Nomifensine

    go.drugbank.com/drugs/DB04821
    ApprovedWithdrawn

    Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. … Approval of the NDA for Merital capsules was withdrawn on March 20, 1992 (see the Federal Register of March 20, 1992 (57 FR 9729)). Also withdrawn from the Canadian and UK markets.

  7. Drug

    Clesrovimab

    go.drugbank.com/drugs/DB18877
    Approved

    to provide passive immunization against RSV infection as an alternative means of protection. … [L53233] As there are no RSV vaccines approved for infant patients, nor are vaccines immediately effective in this population, clesrovimab and similar monoclonal antibodies like [nirsevimab] are designed

  8. Drug

    Proflavine

    go.drugbank.com/drugs/DB01123
    ApprovedInvestigational

    3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings.

    Mixtures: Kerr 100 Triple Dye Dispos-A
  9. Drug

    Aceclofenac

    go.drugbank.com/drugs/DB06736
    Approved

    It is a more commonly prescribed drug in Europe. … In 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, [DB00586], via chemical modification in effort to improve the gastrointestinal tolerability of the drug.

  10. Drug

    Human vaccinia virus immune globulin

    go.drugbank.com/drugs/DB14112
    ApprovedInvestigational

    Most compounds used currently are intravenous formulations, which contain no preservatives - unlike prior intramuscular compounds which contained thiomersal, a mercury derivative preservative that could … Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine