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Irbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigational[L7456,L7459] Irbesartan was granted FDA approval on 30 September 1997.[L7456,L7459] … Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.
Mixtures: KARVEA DUO 300 MG / 5 MG FILM KAPLI TABLET, 28 ADET, KARVEA DUO 150 MG / 5 MG FILM KAPLI TABLET, 28 ADETCategories: Agents Acting on the Renin-Angiotensin SystemAbacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalIn vivo, abacavir sulfate dissociates to its free base, abacavir. … Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring.
Synonyms: {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanolMixtures: ABACAVIR E LAMIVUDINA DR. REDDY'S, ABACAVIR E LAMIVUDINA EGMethyltestosterone
go.drugbank.com/drugs/DB06710ApprovedInvestigationalAlso, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US. … A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies.
Synonyms: 17-beta-Hydroxy-17-methylandrost-4-en-3-one, 17beta-Hydroxy-17-methylandrost-4-en-3-oneAcrivastine
go.drugbank.com/drugs/DB09488ApprovedAcrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D. … As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension
Synonyms: (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acidMixtures: Semprex-D, Semprex DIbrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigational[L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November 2014. … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials.
Synonyms: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-oneEucommia ulmoides bark
go.drugbank.com/drugs/DB14259InvestigationalEucommia ulmoides bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Du Zhong, Du Zhong BarkLevonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigational[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. … Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy.
Mixtures: Aubra EQ, Chateal EQSynonyms: d(-)-Norgestrel, (-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-oneNorethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigationalas an oral contraceptive until 1962. … [A10367] Norethisterone mimics the actions of endogenous [progesterone], albeit with a greater potency,[A188075] and is used on its own or in combination with estrogen derivatives in a variety of applications
Synonyms: 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-oneInternational brands: Primolut-NAEF0117
go.drugbank.com/drugs/DB27675InvestigationalAEF0117 is under investigation in clinical trial NCT05554926 (Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects).
Synonyms: 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one, 3β-(4-methoxybenzyloxy)pregn-5-en-20-one