Acrivastine

DB09488ApprovedSmall moleculeHistamine H1 Antagonists

Acrivastine is an antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion. Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever.

Chemical structure of Acrivastine
Mechanism
Curator reviewed
Primary indication
For the relief of symptoms associated with seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion.Curator reviewed · 1 structured indication
Formula / weight
C22H24N2O2 · 348.4382 g/mol (avg)
First approval
United States, 2008
Code names
BW-825C · BW-A825C
Brand names
  • Semprex-D

Resolves to

Compound
UNIIA20F9XAI7WCAS87848-99-5ChEMBLCHEMBL1224ChEBI83168PubChem5284514KEGGD02760
Clinical / RWD
RxNorm19959ATCR06AX18
Structure
InChIKeyPWACSDKDOHSSQD-IUTFFREVSA-NSMILES[H]\C(CN1CCCC1)=C(\C1=CC=C(C)C=C1)C1=CC=CC(=N1)C(\[H])=C(/[H])C(O)=O
Targets
P35367HRH1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1,082Drug interactionsStructured to mechanism, not free text
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1Structured indicationCondition, population, route and combination as fields, not prose
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3ContraindicationsEach with its own population and attribute set
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6Marketed productsAcross 3 countries and 5 labellers
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1ATC codeIncluding every combination product, plus 10 drug categories
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2+ReferencesStructured and connected to the statements they support
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