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Displaying results 191 - 200 of 10000 in total
  1. Drug

    Guanfacine

    go.drugbank.com/drugs/DB01018
    ApprovedInvestigational

    [L11277] Guanfacine was first described in the literature in 1974.[A189841] Guanfacine was granted FDA approval on 27 October 1986.[L11274] … Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release

    Products: Guanfacine ER, ARİSLOW ER 1 MG UZATILMIŞ SALIMLI TABLET, 7 TABLET
  2. Drug

    Levosulpiride

    go.drugbank.com/drugs/DB16021
    Investigational

    Products: ENDACINE 25 MG SOLUCION EN GOTAS, LEVOSULPIRIDE EG
  3. Drug

    Dinoprostone

    go.drugbank.com/drugs/DB00917
    ApprovedInvestigational

    Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts.

    Synonyms: (15S)-prostaglandin E2, Prostaglandin E2International brands: Prostarmon E
  4. Drug

    Chlorhexidine

    go.drugbank.com/drugs/DB00878
    ApprovedInvestigationalVet approvedWithdrawn

    [L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s. … [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.

    Synonyms: N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamideMixtures: Wart Removal Pen, Wart Removal Pen
  5. Drug

    Hydrocodone

    go.drugbank.com/drugs/DB00956
    ApprovedIllicitInvestigational

    Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is frequently used in cases of severe pain. … [T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain.

    Mixtures: Vicodin ES, Vicodin ESProducts: Zohydro ER, Vantrela ER
  6. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907] … It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative

    Products: PEMETREXED EG, Pemetrexed Actavis 100 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  7. Drug

    Nimesulide

    go.drugbank.com/drugs/DB04743
    ApprovedWithdrawn

    Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries. … Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.

    Products: MESULID SUSPENSION PARA ADMINISTRACIÓN EN GOTAS, NIMESULIDE EG
  8. Drug

    Tiopronin

    go.drugbank.com/drugs/DB06823
    Approved

    Tiopronin is used as a second-line therapy to control the rate of cystine precipitation and excretion, and prevent kidney stone formation. … It is used after a failure of the non-pharmacological first line treatment consisting of increased fluid intake, restriction of sodium and protein, and urinary alkalinization.

    Categories: N-substituted GlycinesProducts: Thiola EC
  9. Drug

    Oxybutynin

    go.drugbank.com/drugs/DB01062
    ApprovedInvestigational

    It is often used as first-line therapy for OAB.[A185990] … efficacy since initial FDA approval in 1975.

    Products: OXIBUTININA EG, Pat-oxybutynin Chloride ER
  10. Target

    Homeobox protein engrailed-2

    go.drugbank.com/bio_entities/BE0004484
    TargetHumans

    Synonyms: Hu-En-2, Homeobox protein en-2